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PCSK9 inhibition and cholesterol homeostasis in insulin producing β-cells
Low-density lipoprotein cholesterol (LDL-C) plays a central role in the pathology of atherosclerotic cardiovascular disease. For decades, the gold standard for LDL-C lowering have been statins, although these drugs carry a moderate risk for the development of new-onset diabetes. The inhibitors of pr...
Autores principales: | Päth, Günter, Perakakis, Nikolaos, Mantzoros, Christos S., Seufert, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756761/ https://www.ncbi.nlm.nih.gov/pubmed/36527064 http://dx.doi.org/10.1186/s12944-022-01751-6 |
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