Gut microbiota in ischemic stroke: Where we stand and challenges ahead

Gut microbiota is increasingly recognized to affect host health and disease, including ischemic stroke (IS). Here, we systematically review the current understanding linking gut microbiota as well as the associated metabolites to the pathogenesis of IS (e.g., oxidative stress, apoptosis, and neuroin...

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Detalles Bibliográficos
Autores principales: Long, Jiaxin, Wang, Jinlong, Li, Yang, Chen, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756810/
https://www.ncbi.nlm.nih.gov/pubmed/36532541
http://dx.doi.org/10.3389/fnut.2022.1008514
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author Long, Jiaxin
Wang, Jinlong
Li, Yang
Chen, Shuai
author_facet Long, Jiaxin
Wang, Jinlong
Li, Yang
Chen, Shuai
author_sort Long, Jiaxin
collection PubMed
description Gut microbiota is increasingly recognized to affect host health and disease, including ischemic stroke (IS). Here, we systematically review the current understanding linking gut microbiota as well as the associated metabolites to the pathogenesis of IS (e.g., oxidative stress, apoptosis, and neuroinflammation). Of relevance, we highlight that the implications of gut microbiota-dependent intervention could be harnessed in orchestrating IS.
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spelling pubmed-97568102022-12-17 Gut microbiota in ischemic stroke: Where we stand and challenges ahead Long, Jiaxin Wang, Jinlong Li, Yang Chen, Shuai Front Nutr Nutrition Gut microbiota is increasingly recognized to affect host health and disease, including ischemic stroke (IS). Here, we systematically review the current understanding linking gut microbiota as well as the associated metabolites to the pathogenesis of IS (e.g., oxidative stress, apoptosis, and neuroinflammation). Of relevance, we highlight that the implications of gut microbiota-dependent intervention could be harnessed in orchestrating IS. Frontiers Media S.A. 2022-12-01 /pmc/articles/PMC9756810/ /pubmed/36532541 http://dx.doi.org/10.3389/fnut.2022.1008514 Text en Copyright © 2022 Long, Wang, Li and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Long, Jiaxin
Wang, Jinlong
Li, Yang
Chen, Shuai
Gut microbiota in ischemic stroke: Where we stand and challenges ahead
title Gut microbiota in ischemic stroke: Where we stand and challenges ahead
title_full Gut microbiota in ischemic stroke: Where we stand and challenges ahead
title_fullStr Gut microbiota in ischemic stroke: Where we stand and challenges ahead
title_full_unstemmed Gut microbiota in ischemic stroke: Where we stand and challenges ahead
title_short Gut microbiota in ischemic stroke: Where we stand and challenges ahead
title_sort gut microbiota in ischemic stroke: where we stand and challenges ahead
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756810/
https://www.ncbi.nlm.nih.gov/pubmed/36532541
http://dx.doi.org/10.3389/fnut.2022.1008514
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AT chenshuai gutmicrobiotainischemicstrokewherewestandandchallengesahead

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