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Cells with stochastically increased methyltransferase to restriction endonuclease ratio provide an entry for bacteriophage into protected cell population

The action of Type II restriction–modification (RM) systems depends on restriction endonuclease (REase), which cleaves foreign DNA at specific sites, and methyltransferase (MTase), which protects host genome from restriction by methylating the same sites. We here show that protection from phage infe...

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Detalles Bibliográficos
Autores principales: Kirillov, Alexander, Morozova, Natalia, Kozlova, Svetlana, Polinovskaya, Vasilisa, Smirnov, Sergey, Khodorkovskii, Mikhail, Zeng, Lanying, Ispolatov, Yaroslav, Severinov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757035/
https://www.ncbi.nlm.nih.gov/pubmed/36477901
http://dx.doi.org/10.1093/nar/gkac1124