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Cells with stochastically increased methyltransferase to restriction endonuclease ratio provide an entry for bacteriophage into protected cell population
The action of Type II restriction–modification (RM) systems depends on restriction endonuclease (REase), which cleaves foreign DNA at specific sites, and methyltransferase (MTase), which protects host genome from restriction by methylating the same sites. We here show that protection from phage infe...
Autores principales: | Kirillov, Alexander, Morozova, Natalia, Kozlova, Svetlana, Polinovskaya, Vasilisa, Smirnov, Sergey, Khodorkovskii, Mikhail, Zeng, Lanying, Ispolatov, Yaroslav, Severinov, Konstantin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757035/ https://www.ncbi.nlm.nih.gov/pubmed/36477901 http://dx.doi.org/10.1093/nar/gkac1124 |
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