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Spontaneous binding of single-stranded RNAs to RRM proteins visualized by unbiased atomistic simulations with a rescaled RNA force field

Recognition of single-stranded RNA (ssRNA) by RNA recognition motif (RRM) domains is an important class of protein–RNA interactions. Many such complexes were characterized using nuclear magnetic resonance (NMR) and/or X-ray crystallography techniques, revealing ensemble-averaged pictures of the boun...

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Detalles Bibliográficos
Autores principales: Krepl, Miroslav, Pokorná, Pavlína, Mlýnský, Vojtěch, Stadlbauer, Petr, Šponer, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757038/
https://www.ncbi.nlm.nih.gov/pubmed/36454011
http://dx.doi.org/10.1093/nar/gkac1106