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PARG and BRCA1–BARD1 cooperative function regulates DNA repair pathway choice during gametogenesis

Meiotic chromosome segregation relies on programmed DNA double-strand break induction. These are in turn repaired by homologous recombination, generating physical attachments between the parental chromosomes called crossovers. A subset of breaks yields recombinant outcomes, while crossover-independe...

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Detalles Bibliográficos
Autores principales: Trivedi, Shalini, Blazícková, Jitka, Silva, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757042/
https://www.ncbi.nlm.nih.gov/pubmed/36478097
http://dx.doi.org/10.1093/nar/gkac1153

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