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PARG and BRCA1–BARD1 cooperative function regulates DNA repair pathway choice during gametogenesis
Meiotic chromosome segregation relies on programmed DNA double-strand break induction. These are in turn repaired by homologous recombination, generating physical attachments between the parental chromosomes called crossovers. A subset of breaks yields recombinant outcomes, while crossover-independe...
Autores principales: | Trivedi, Shalini, Blazícková, Jitka, Silva, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757042/ https://www.ncbi.nlm.nih.gov/pubmed/36478097 http://dx.doi.org/10.1093/nar/gkac1153 |
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