Cargando…
KLF4 inhibits early neural differentiation of ESCs by coordinating specific 3D chromatin structure
Neural differentiation of embryonic stem cells (ESCs) requires precisely orchestrated gene regulation, a process governed in part by changes in 3D chromatin structure. How these changes regulate gene expression in this context remains unclear. In this study, we observed enrichment of the transcripti...
Autores principales: | Bi, Jinfang, Wang, Wenbin, Zhang, Meng, Zhang, Baoying, Liu, Man, Su, Guangsong, Chen, Fuquan, Chen, Bohan, Shi, Tengfei, Zheng, Yaoqiang, Zhao, Xueyuan, Zhao, Zhongfang, Shi, Jiandang, Li, Peng, Zhang, Lei, Lu, Wange |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757050/ https://www.ncbi.nlm.nih.gov/pubmed/36477888 http://dx.doi.org/10.1093/nar/gkac1118 |
Ejemplares similares
-
Enhancer architecture-dependent multilayered transcriptional regulation orchestrates RA signaling-induced early lineage differentiation of ESCs
por: Su, Guangsong, et al.
Publicado: (2021) -
A distal enhancer maintaining Hoxa1 expression orchestrates retinoic acid-induced early ESCs differentiation
por: Su, Guangsong, et al.
Publicado: (2019) -
CTCF-binding element regulates ESC differentiation via orchestrating long-range chromatin interaction between enhancers and HoxA
por: Su, Guangsong, et al.
Publicado: (2021) -
Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing
por: Choi, Jongkyu, et al.
Publicado: (2011) -
Structural basis for Klf4 recognition of methylated DNA
por: Liu, Yiwei, et al.
Publicado: (2014)