β-Endorphin mediates radiation therapy fatigue

Fatigue is a common adverse effect of external beam radiation therapy in cancer patients. Mechanisms causing radiation fatigue remain unclear, although linkage to skin irradiation has been suggested. β-Endorphin, an endogenous opioid, is synthesized in skin following genotoxic ultraviolet irradiatio...

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Detalles Bibliográficos
Autores principales: Hermann, Andrea L., Fell, Gillian L., Kemény, Lajos V., Fung, Claire Y., Held, Kathryn D., Biggs, Peter J., Rivera, Phillip D., Bilbo, Staci D., Igras, Vivien, Willers, Henning, Kung, Jong, Gheorghiu, Liliana, Hideghéty, Katalin, Mao, Jianren, Woolf, Clifford J., Fisher, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757747/
https://www.ncbi.nlm.nih.gov/pubmed/36525492
http://dx.doi.org/10.1126/sciadv.abn6025

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