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Mechanisms of ion selectivity and throughput in the mitochondrial calcium uniporter
The mitochondrial calcium uniporter, which regulates aerobic metabolism by catalyzing mitochondrial Ca(2+) influx, is arguably the most selective ion channel known. The mechanisms for this exquisite Ca(2+) selectivity have not been defined. Here, using a reconstituted system, we study the electrical...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757755/ https://www.ncbi.nlm.nih.gov/pubmed/36525497 http://dx.doi.org/10.1126/sciadv.ade1516 |