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Rapid and inexpensive purification of adenovirus vectors using an optimised aqueous two-phase technology
Adenoviruses (AdVs) are used as gene therapy vectors to treat human diseases and as vaccines against COVID-19. AdVs are produced by transfecting human embryonic kidney 239 (HEK293) or PER.C6 virus producer cells with AdV plasmid vectors or infecting these cells withcell lysates containing replicatio...
Autores principales: | Suleman, Saqlain, Schrubaji, Kuteiba, Filippou, Chrysovalanto, Ignatova, Svetlana, Hewitson, Peter, Huddleston, Jonathan, Karda, Rajvinder, Waddington, Simon N., Themis, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757833/ https://www.ncbi.nlm.nih.gov/pubmed/34626684 http://dx.doi.org/10.1016/j.jviromet.2021.114305 |
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