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Long term intrinsic cycling in human life course antibody responses to influenza A(H3N2): an observational and modeling study
BACKGROUND: Over a life course, human adaptive immunity to antigenically mutable pathogens exhibits competitive and facilitative interactions. We hypothesize that such interactions may lead to cyclic dynamics in immune responses over a lifetime. METHODS: To investigate the cyclic behavior, we analyz...
Autores principales: | Yang, Bingyi, García-Carreras, Bernardo, Lessler, Justin, Read, Jonathan M, Zhu, Huachen, Metcalf, C Jessica E, Hay, James A, Kwok, Kin O, Shen, Ruiyun, Jiang, Chao Q, Guan, Yi, Riley, Steven, Cummings, Derek A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757834/ https://www.ncbi.nlm.nih.gov/pubmed/36458815 http://dx.doi.org/10.7554/eLife.81457 |
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