Investigating mitochondrial fission, fusion, and autophagy in retinal pigment epithelium from donors with age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in developed countries, characterized by the death of retinal pigment epithelial (RPE) cells and photoreceptors. Previous studies report an accumulation of damaged and dysfunctional mitochondria in RPE of human don...

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Detalles Bibliográficos
Autores principales: Fisher, Cody R., Shaaeli, Adam A., Ebeling, Mara C., Montezuma, Sandra R., Ferrington, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758189/
https://www.ncbi.nlm.nih.gov/pubmed/36526679
http://dx.doi.org/10.1038/s41598-022-26012-5

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