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Clinical outcomes following surgical management of deep infiltrating endometriosis

The main aim of the study was to evaluate severe post-operative complications following deep endometriosis surgery in a tertiary referral centre. This is a retrospective cohort study that included women who had surgery for deep infiltrating endometriosis between 1st January 2013 and 31st December 20...

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Autores principales: Leborne, Perrine, Huberlant, Stephanie, Masia, Florent, de Tayrac, Renaud, Letouzey, Vincent, Allegre, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758215/
https://www.ncbi.nlm.nih.gov/pubmed/36526707
http://dx.doi.org/10.1038/s41598-022-25751-9
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author Leborne, Perrine
Huberlant, Stephanie
Masia, Florent
de Tayrac, Renaud
Letouzey, Vincent
Allegre, Lucie
author_facet Leborne, Perrine
Huberlant, Stephanie
Masia, Florent
de Tayrac, Renaud
Letouzey, Vincent
Allegre, Lucie
author_sort Leborne, Perrine
collection PubMed
description The main aim of the study was to evaluate severe post-operative complications following deep endometriosis surgery in a tertiary referral centre. This is a retrospective cohort study that included women who had surgery for deep infiltrating endometriosis between 1st January 2013 and 31st December 2019. Endometriosis was diagnosed based on clinical, imaging and histological parameters. We evaluated the rates of post-operative complications, potential risk factors for such complications and postoperative pregnancy rates. A total of 165 patients were included in the final analysis. The median follow-up was 63 (25–106) months. Thirty-seven patients (22.42%) had hysterectomy, 60 (36.81%) had ureterolysis and 44 (26.67%) had colorectal surgery. The overall and severe rates of post-operative complications were 16.20% (n = 23) and 2.42% (n = 4) respectively. Of the variables assessed, operative time and age were the only statistically significant risk factor for complications on multivariate analysis. Among women operated on for infertility, 34.5% (n = 20/58) got pregnant following surgery with 30% of these spontaneously. This study demonstrates acceptable overall and severe post-operative complications and pregnancy rates after deep endometriosis surgery. This information should help clinicians when counselling women to enable them making an informed choice about their management.
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spelling pubmed-97582152022-12-18 Clinical outcomes following surgical management of deep infiltrating endometriosis Leborne, Perrine Huberlant, Stephanie Masia, Florent de Tayrac, Renaud Letouzey, Vincent Allegre, Lucie Sci Rep Article The main aim of the study was to evaluate severe post-operative complications following deep endometriosis surgery in a tertiary referral centre. This is a retrospective cohort study that included women who had surgery for deep infiltrating endometriosis between 1st January 2013 and 31st December 2019. Endometriosis was diagnosed based on clinical, imaging and histological parameters. We evaluated the rates of post-operative complications, potential risk factors for such complications and postoperative pregnancy rates. A total of 165 patients were included in the final analysis. The median follow-up was 63 (25–106) months. Thirty-seven patients (22.42%) had hysterectomy, 60 (36.81%) had ureterolysis and 44 (26.67%) had colorectal surgery. The overall and severe rates of post-operative complications were 16.20% (n = 23) and 2.42% (n = 4) respectively. Of the variables assessed, operative time and age were the only statistically significant risk factor for complications on multivariate analysis. Among women operated on for infertility, 34.5% (n = 20/58) got pregnant following surgery with 30% of these spontaneously. This study demonstrates acceptable overall and severe post-operative complications and pregnancy rates after deep endometriosis surgery. This information should help clinicians when counselling women to enable them making an informed choice about their management. Nature Publishing Group UK 2022-12-16 /pmc/articles/PMC9758215/ /pubmed/36526707 http://dx.doi.org/10.1038/s41598-022-25751-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Leborne, Perrine
Huberlant, Stephanie
Masia, Florent
de Tayrac, Renaud
Letouzey, Vincent
Allegre, Lucie
Clinical outcomes following surgical management of deep infiltrating endometriosis
title Clinical outcomes following surgical management of deep infiltrating endometriosis
title_full Clinical outcomes following surgical management of deep infiltrating endometriosis
title_fullStr Clinical outcomes following surgical management of deep infiltrating endometriosis
title_full_unstemmed Clinical outcomes following surgical management of deep infiltrating endometriosis
title_short Clinical outcomes following surgical management of deep infiltrating endometriosis
title_sort clinical outcomes following surgical management of deep infiltrating endometriosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758215/
https://www.ncbi.nlm.nih.gov/pubmed/36526707
http://dx.doi.org/10.1038/s41598-022-25751-9
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