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Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump
OBJECTIVES: To determine whether surgical technique has an effect on prognosis in coronary artery bypass grafting (CABG). DESIGN: Retrospective observational. SETTING: Single center. PARTICIPANTS: All the off-pump (OPCABG) and on-pump (ONCABG) patients at Turku University Central Hospital in 2018. I...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758289/ https://www.ncbi.nlm.nih.gov/pubmed/36536727 http://dx.doi.org/10.1016/j.amsu.2022.104812 |
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author | Rantanen, Matias Yousif, Rizgar Kallioinen, Minna Hynninen, Ville-Veikko Peltoniemi, Marko Söderholm, Oki Saarikoski, Tuukka Anttila, Vesa Aittokallio, Jenni |
author_facet | Rantanen, Matias Yousif, Rizgar Kallioinen, Minna Hynninen, Ville-Veikko Peltoniemi, Marko Söderholm, Oki Saarikoski, Tuukka Anttila, Vesa Aittokallio, Jenni |
author_sort | Rantanen, Matias |
collection | PubMed |
description | OBJECTIVES: To determine whether surgical technique has an effect on prognosis in coronary artery bypass grafting (CABG). DESIGN: Retrospective observational. SETTING: Single center. PARTICIPANTS: All the off-pump (OPCABG) and on-pump (ONCABG) patients at Turku University Central Hospital in 2018. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: After propensity score matching, perioperative, 1-year and 3-year mortality did not differ between the groups. The ONCABG patients received more allogenic red blood cells (1.3 vs. 0.6 units, p = 0.020), autologous red blood cells (564 vs. 285 ml, p < 0.001) and crystalloids (3388 vs. 2808 ml, p < 0.001), and had higher postoperative values of troponin T (581 vs. 222, p = 0.001) and lactate (1.69 vs. 1.23, p < 0.001) than the OPCABG patients. CONCLUSIONS: The both techniques seem equally safe. However, there may be some benefits to avoiding using a heart-lung machine, such as lower infused fluid volumes. Myocardial damage may also be milder and postoperative hemodynamics more balanced in OPCABG patients, based on lower levels of troponin T and lactate. |
format | Online Article Text |
id | pubmed-9758289 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-97582892022-12-18 Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump Rantanen, Matias Yousif, Rizgar Kallioinen, Minna Hynninen, Ville-Veikko Peltoniemi, Marko Söderholm, Oki Saarikoski, Tuukka Anttila, Vesa Aittokallio, Jenni Ann Med Surg (Lond) Cross-sectional Study OBJECTIVES: To determine whether surgical technique has an effect on prognosis in coronary artery bypass grafting (CABG). DESIGN: Retrospective observational. SETTING: Single center. PARTICIPANTS: All the off-pump (OPCABG) and on-pump (ONCABG) patients at Turku University Central Hospital in 2018. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: After propensity score matching, perioperative, 1-year and 3-year mortality did not differ between the groups. The ONCABG patients received more allogenic red blood cells (1.3 vs. 0.6 units, p = 0.020), autologous red blood cells (564 vs. 285 ml, p < 0.001) and crystalloids (3388 vs. 2808 ml, p < 0.001), and had higher postoperative values of troponin T (581 vs. 222, p = 0.001) and lactate (1.69 vs. 1.23, p < 0.001) than the OPCABG patients. CONCLUSIONS: The both techniques seem equally safe. However, there may be some benefits to avoiding using a heart-lung machine, such as lower infused fluid volumes. Myocardial damage may also be milder and postoperative hemodynamics more balanced in OPCABG patients, based on lower levels of troponin T and lactate. Elsevier 2022-11-09 /pmc/articles/PMC9758289/ /pubmed/36536727 http://dx.doi.org/10.1016/j.amsu.2022.104812 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Cross-sectional Study Rantanen, Matias Yousif, Rizgar Kallioinen, Minna Hynninen, Ville-Veikko Peltoniemi, Marko Söderholm, Oki Saarikoski, Tuukka Anttila, Vesa Aittokallio, Jenni Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump |
title | Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump |
title_full | Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump |
title_fullStr | Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump |
title_full_unstemmed | Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump |
title_short | Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump |
title_sort | retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: off-pump versus on-pump |
topic | Cross-sectional Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758289/ https://www.ncbi.nlm.nih.gov/pubmed/36536727 http://dx.doi.org/10.1016/j.amsu.2022.104812 |
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