Cargando…

Extension of microglial activation is associated with epilepsy and cognitive dysfunction in Tuberous sclerosis complex: A TSPO-PET study

BACKGROUND AND OBJECTIVES: Neuroinflammation contributes to the severity of various neurological disorders, including epilepsy. Tuberous sclerosis complex (TSC) is a condition that results in the overactivation of the mammalian target of rapamycin (mTOR) pathway, which has been linked to the activat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kagitani-Shimono, Kuriko, Kato, Hiroki, Soeda, Fumihiko, Iwatani, Yoshiko, Mukai, Masashi, Ogawa, Katsuhiro, Tominaga, Koji, Nabatame, Shin, Taniike, Masako
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758490/ https://www.ncbi.nlm.nih.gov/pubmed/36521371 http://dx.doi.org/10.1016/j.nicl.2022.103288

Ejemplares similares

Abnormal White Matter Microstructure in the Limbic System Is Associated With Tuberous Sclerosis Complex-Associated Neuropsychiatric Disorders
por: Sato, Akemi, et al.
Publicado: (2022)

Clinical evaluation of neuroinflammation in child-onset focal epilepsy: a translocator protein PET study
por: Kagitani-Shimono, Kuriko, et al.
Publicado: (2021)

Clinical Factors Related to Outcomes in Pediatric Epilepsy Surgery: Insight into Predictors of Poor Surgical Outcome
por: OSHINO, Satoru, et al.
Publicado: (2023)

Examining normative values using the Cambridge neuropsychological test automated battery and developmental traits of executive functions among elementary school-aged children in Japan
por: Aoki, Sho, et al.
Publicado: (2023)

Lesser suppression of response to bright visual stimuli and visual abnormality in children with autism spectrum disorder: a magnetoencephalographic study
por: Aoki, Sho, et al.
Publicado: (2019)

White Matter Tract-Cognitive Relationships in Children with High-Functioning Autism Spectrum Disorder
por: Kato, Yoko, et al.
Publicado: (2019)

Anti-inflammatory therapy by ibudilast, a phosphodiesterase inhibitor, in demyelination of twitcher, a genetic demyelination model
por: Kagitani-Shimono, Kuriko, et al.
Publicado: (2005)

Progressively Increased M50 Responses to Repeated Sounds in Autism Spectrum Disorder with Auditory Hypersensitivity: A Magnetoencephalographic Study
por: Matsuzaki, Junko, et al.
Publicado: (2014)

Delayed Mismatch Field Latencies in Autism Spectrum Disorder with Abnormal Auditory Sensitivity: A Magnetoencephalographic Study
por: Matsuzaki, Junko, et al.
Publicado: (2017)

A preliminary study of sleep spindles across non-rapid eye movement sleep stages in children with autism spectrum disorder
por: Kawahara, Midori, et al.
Publicado: (2022)

Aberrant Cerebellar–Cerebral Functional Connectivity in Children and Adolescents With Autism Spectrum Disorder
por: Hanaie, Ryuzo, et al.
Publicado: (2018)

Structural brain abnormalities in children and adolescents with comorbid autism spectrum disorder and attention-deficit/hyperactivity disorder
por: Mizuno, Yoshifumi, et al.
Publicado: (2019)

Astrocytic TSPO Upregulation Appears Before Microglial TSPO in Alzheimer’s Disease
por: Tournier, Benjamin B., et al.
Publicado: (2020)

Atypical structural connectivity of language networks in autism spectrum disorder: A meta‐analysis of diffusion tensor imaging studies
por: Li, Min, et al.
Publicado: (2022)

PET Imaging of Microglial Activation—Beyond Targeting TSPO
por: Janssen, Bieneke, et al.
Publicado: (2018)

TSPO PET Imaging: From Microglial Activation to Peripheral Sterile Inflammatory Diseases?
por: Largeau, Bérenger, et al.
Publicado: (2017)

Translocator Protein 18 kDa (TSPO) Deficiency Inhibits Microglial Activation and Impairs Mitochondrial Function
por: Yao, Rumeng, et al.
Publicado: (2020)

TSPO PET upregulation predicts epileptic phenotype at disease onset independently from chronic TSPO expression in a rat model of temporal lobe epilepsy
por: Bertoglio, Daniele, et al.
Publicado: (2021)

Binding of NIR-conPK and NIR-6T to Astrocytomas and Microglial Cells: Evidence for a Protein Related to TSPO
por: Sexton, Michelle, et al.
Publicado: (2009)

Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis
por: Karlstetter, Marcus, et al.
Publicado: (2014)

Child Developmental MRI (CDM) project: protocol for a multi-centre, cross-sectional study on elucidating the pathophysiology of attention-deficit/hyperactivity disorder and autism spectrum disorder through a multi-dimensional approach
por: Yamashita, Masatoshi, et al.
Publicado: (2023)

TSPO expression in brain tumours: is TSPO a target for brain tumour imaging?
por: Roncaroli, Federico, et al.
Publicado: (2016)

Promising Effect of a New Ketogenic Diet Regimen in Patients with Advanced Cancer
por: Hagihara, Keisuke, et al.
Publicado: (2020)

Novel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex
por: Mühlebner, Angelika, et al.
Publicado: (2016)

Autism and Epilepsy in Patients With Tuberous Sclerosis Complex
por: Specchio, Nicola, et al.
Publicado: (2020)

Epilepsy in adult patients with tuberous sclerosis complex
por: Vignoli, Aglaia, et al.
Publicado: (2021)

Which is the Most Appropriate Disconnection Surgery for Refractory Epilepsy in Childhood?
por: Kishima, Haruhiko, et al.
Publicado: (2013)

Inhibitory Effects of the Two Novel TSPO Ligands 2-Cl-MGV-1 and MGV-1 on LPS-induced Microglial Activation
por: Monga, Sheelu, et al.
Publicado: (2019)

TSPO imaging in parkinsonian disorders
por: Gerhard, Alexander
Publicado: (2016)

A case of tuberous sclerosis complex revealed by epilepsy
por: Koné, Noukhoum, et al.
Publicado: (2017)

Is autism driven by epilepsy in infants with Tuberous Sclerosis Complex?
por: Moavero, Romina, et al.
Publicado: (2020)

TLR7 activation in epilepsy of tuberous sclerosis complex
por: Dombkowski, Alan A., et al.
Publicado: (2019)

Microglial contributions to aberrant neurogenesis and pathophysiology of epilepsy
por: Victor, Tanya R., et al.
Publicado: (2020)

Emerging Roles for Microglial Phagocytic Signaling in Epilepsy
por: Wyatt-Johnson, Season K., et al.
Publicado: (2019)

Microglial Cells in Epilepsy: Not That Bad After All?
por: Jones, Nigel C.
Publicado: (2020)

The Efficacy of the Novel TSPO Ligands 2-Cl-MGV-1 and 2,4-Di-Cl-MGV-1 Compared to the Classical TSPO Ligand PK 11195 to Counteract the Release of Chemokines from LPS-Stimulated BV-2 Microglial Cells
por: Monga, Sheelu, et al.
Publicado: (2020)

An Updated View of Translocator Protein (TSPO)
por: Denora, Nunzio, et al.
Publicado: (2017)

The role of TSPO PET in assessing neuroinflammation
por: Crawshaw, Ania A., et al.
Publicado: (2017)

Membrane-embedded TSPO: an NMR view
por: Rivière, Gwladys, et al.
Publicado: (2020)

Supervised clustering for TSPO PET imaging
por: Schubert, Julia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5e7jnrr30e2gagjrmnq9ptoro5