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Astragaloside IV attenuates IL-1β-induced intervertebral disc degeneration through inhibition of the NF-κB pathway

BACKGROUND: Intervertebral disc degeneration (IDD) is the main cause of low back pain. Patients with low back pain may experience significant socio-economic burdens and decreased productivity. Previous studies have shown that inflammation is one of the main causes of IDD. Astragaloside IV (AS IV), a...

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Detalles Bibliográficos
Autores principales: Tian, Yueyang, Chu, Xu, Huang, Qia, Guo, Xing, Xue, Yuan, Deng, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758796/
https://www.ncbi.nlm.nih.gov/pubmed/36527065
http://dx.doi.org/10.1186/s13018-022-03438-1