Emerging roles and mechanisms of miR-206 in human disorders: a comprehensive review

As a member of the miR-1 family, miR-206 is located between IL-17 and PKHD1 genes in human. This miRNA has been shown to be involved in the pathogenic processes in a variety of human disorders including cancers, amyotrophic lateral sclerosis, Alzheimer’s disease, atherosclerosis, bronchopulmonary dy...

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Autores principales: Khalilian, Sheyda, Hosseini Imani, Seyedeh Zahra, Ghafouri-Fard, Soudeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758816/
https://www.ncbi.nlm.nih.gov/pubmed/36528620
http://dx.doi.org/10.1186/s12935-022-02833-2
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author Khalilian, Sheyda
Hosseini Imani, Seyedeh Zahra
Ghafouri-Fard, Soudeh
author_facet Khalilian, Sheyda
Hosseini Imani, Seyedeh Zahra
Ghafouri-Fard, Soudeh
author_sort Khalilian, Sheyda
collection PubMed
description As a member of the miR-1 family, miR-206 is located between IL-17 and PKHD1 genes in human. This miRNA has been shown to be involved in the pathogenic processes in a variety of human disorders including cancers, amyotrophic lateral sclerosis, Alzheimer’s disease, atherosclerosis, bronchopulmonary dysplasia, coronary artery disease, chronic obstructive pulmonary disease, epilepsy, nonalcoholic fatty liver disease, Hirschsprung disease, muscular dystrophies, pulmonary arterial hypertension, sepsis and ulcerative colitis. In the current review, we summarize the role of miR-206 in both malignant and non-malignant situations and explain its possible therapeutic implications.
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spelling pubmed-97588162022-12-18 Emerging roles and mechanisms of miR-206 in human disorders: a comprehensive review Khalilian, Sheyda Hosseini Imani, Seyedeh Zahra Ghafouri-Fard, Soudeh Cancer Cell Int Review As a member of the miR-1 family, miR-206 is located between IL-17 and PKHD1 genes in human. This miRNA has been shown to be involved in the pathogenic processes in a variety of human disorders including cancers, amyotrophic lateral sclerosis, Alzheimer’s disease, atherosclerosis, bronchopulmonary dysplasia, coronary artery disease, chronic obstructive pulmonary disease, epilepsy, nonalcoholic fatty liver disease, Hirschsprung disease, muscular dystrophies, pulmonary arterial hypertension, sepsis and ulcerative colitis. In the current review, we summarize the role of miR-206 in both malignant and non-malignant situations and explain its possible therapeutic implications. BioMed Central 2022-12-17 /pmc/articles/PMC9758816/ /pubmed/36528620 http://dx.doi.org/10.1186/s12935-022-02833-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Khalilian, Sheyda
Hosseini Imani, Seyedeh Zahra
Ghafouri-Fard, Soudeh
Emerging roles and mechanisms of miR-206 in human disorders: a comprehensive review
title Emerging roles and mechanisms of miR-206 in human disorders: a comprehensive review
title_full Emerging roles and mechanisms of miR-206 in human disorders: a comprehensive review
title_fullStr Emerging roles and mechanisms of miR-206 in human disorders: a comprehensive review
title_full_unstemmed Emerging roles and mechanisms of miR-206 in human disorders: a comprehensive review
title_short Emerging roles and mechanisms of miR-206 in human disorders: a comprehensive review
title_sort emerging roles and mechanisms of mir-206 in human disorders: a comprehensive review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758816/
https://www.ncbi.nlm.nih.gov/pubmed/36528620
http://dx.doi.org/10.1186/s12935-022-02833-2
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