A novel lncRNA MDHDH suppresses glioblastoma multiforme by acting as a scaffold for MDH2 and PSMA1 to regulate NAD+ metabolism and autophagy

BACKGROUND: To identify potential targets related to nicotinamide adenine dinucleotide (NAD+) metabolism in gliomas, we used RNA immunoprecipitation to identify a novel long noncoding RNA renamed malate dehydrogenase degradation helper (MDHDH) (NONCODE annotation ID: NONHSAT138800.2, NCBI Reference...

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Detalles Bibliográficos
Autores principales: He, Dong, Xin, Tao, Pang, Bo, Sun, Jun, Liu, Zi Hao, Qin, Zhen, Ji, Xiao Shuai, Yang, Fan, Wei, Yan Bang, Wang, Zi Xiao, Gao, Jia Jia, Pang, Qi, Liu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758949/
https://www.ncbi.nlm.nih.gov/pubmed/36527092
http://dx.doi.org/10.1186/s13046-022-02543-7

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