Cargando…
Sputum from patients with primary ciliary dyskinesia contains high numbers of dysfunctional neutrophils and inhibits efferocytosis
BACKGROUND: Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by recurrent airway infection and inflammation. There is no cure for PCD and to date there are no specific treatments available. Neutrophils are a crucial part of the immune system and are known to be dysfunctional in m...
Autores principales: | Blanter, Marfa, Cockx, Maaike, Wittebols, Liesel, Abouelasrar Salama, Sara, De Bondt, Mirre, Berghmans, Nele, Pörtner, Noëmie, Vanbrabant, Lotte, Lorent, Natalie, Gouwy, Mieke, Boon, Mieke, Struyf, Sofie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758951/ https://www.ncbi.nlm.nih.gov/pubmed/36528664 http://dx.doi.org/10.1186/s12931-022-02280-7 |
Ejemplares similares
-
The Antimicrobial Activity of Peripheral Blood Neutrophils Is Altered in Patients with Primary Ciliary Dyskinesia
por: Cockx, Maaike, et al.
Publicado: (2021) -
Method Matters: Effect of Purification Technology on Neutrophil Phenotype and Function
por: Blanter, Marfa, et al.
Publicado: (2022) -
Neutrophils from Patients with Primary Ciliary Dyskinesia Display Reduced Chemotaxis to CXCR2 Ligands
por: Cockx, Maaike, et al.
Publicado: (2017) -
Matrix Metalloproteinase-9-Generated COOH-, but Not NH(2)-Terminal Fragments of Serum Amyloid A1 Retain Potentiating Activity in Neutrophil Migration to CXCL8, With Loss of Direct Chemotactic and Cytokine-Inducing Capacity
por: Gouwy, Mieke, et al.
Publicado: (2018) -
Studying Neutrophil Function in vitro: Cell Models and Environmental Factors
por: Blanter, Marfa, et al.
Publicado: (2021)