Progress of Research into the Interleukin-1 Family in Cardiovascular Disease

Inflammatory factors, such as the IL-1 family, are generally acknowledged to be involved in systemic diseases and IL-1α and IL-1β, in particular, have been linked to cardiovascular disease with IL-18, IL-33, IL-36, IL-37 and IL-38 yet to be explored. The current review aims to summarize mechanisms o...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Zimin, Luo, Cheng, Zheng, Baoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759010/
https://www.ncbi.nlm.nih.gov/pubmed/36536642
http://dx.doi.org/10.2147/JIR.S390915
_version_ 1784852160464289792
author Wu, Zimin
Luo, Cheng
Zheng, Baoshi
author_facet Wu, Zimin
Luo, Cheng
Zheng, Baoshi
author_sort Wu, Zimin
collection PubMed
description Inflammatory factors, such as the IL-1 family, are generally acknowledged to be involved in systemic diseases and IL-1α and IL-1β, in particular, have been linked to cardiovascular disease with IL-18, IL-33, IL-36, IL-37 and IL-38 yet to be explored. The current review aims to summarize mechanisms of IL-18, IL-33, IL-36, IL-37 and IL-38 in myocardial infarction, hypertension, arrhythmia, valvular disease and aneurysm and to explore the potential for cardiovascular disease treatment strategies and discuss future directions for prevention and treatment.
format Online
Article
Text
id pubmed-9759010
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-97590102022-12-18 Progress of Research into the Interleukin-1 Family in Cardiovascular Disease Wu, Zimin Luo, Cheng Zheng, Baoshi J Inflamm Res Review Inflammatory factors, such as the IL-1 family, are generally acknowledged to be involved in systemic diseases and IL-1α and IL-1β, in particular, have been linked to cardiovascular disease with IL-18, IL-33, IL-36, IL-37 and IL-38 yet to be explored. The current review aims to summarize mechanisms of IL-18, IL-33, IL-36, IL-37 and IL-38 in myocardial infarction, hypertension, arrhythmia, valvular disease and aneurysm and to explore the potential for cardiovascular disease treatment strategies and discuss future directions for prevention and treatment. Dove 2022-12-13 /pmc/articles/PMC9759010/ /pubmed/36536642 http://dx.doi.org/10.2147/JIR.S390915 Text en © 2022 Wu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Wu, Zimin
Luo, Cheng
Zheng, Baoshi
Progress of Research into the Interleukin-1 Family in Cardiovascular Disease
title Progress of Research into the Interleukin-1 Family in Cardiovascular Disease
title_full Progress of Research into the Interleukin-1 Family in Cardiovascular Disease
title_fullStr Progress of Research into the Interleukin-1 Family in Cardiovascular Disease
title_full_unstemmed Progress of Research into the Interleukin-1 Family in Cardiovascular Disease
title_short Progress of Research into the Interleukin-1 Family in Cardiovascular Disease
title_sort progress of research into the interleukin-1 family in cardiovascular disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759010/
https://www.ncbi.nlm.nih.gov/pubmed/36536642
http://dx.doi.org/10.2147/JIR.S390915
work_keys_str_mv AT wuzimin progressofresearchintotheinterleukin1familyincardiovasculardisease
AT luocheng progressofresearchintotheinterleukin1familyincardiovasculardisease
AT zhengbaoshi progressofresearchintotheinterleukin1familyincardiovasculardisease

Ejemplares similares