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Engineering antibody and protein therapeutics to cross the blood–brain barrier
Diseases in the central nervous system (CNS) are often difficult to treat. Antibody- and protein-based therapeutics hold huge promises in CNS disease treatment. However, proteins are restricted from entering the CNS by the blood–brain barrier (BBB). To achieve enhanced BBB crossing, antibody-based c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759110/ https://www.ncbi.nlm.nih.gov/pubmed/36540309 http://dx.doi.org/10.1093/abt/tbac028 |