Engineering antibody and protein therapeutics to cross the blood–brain barrier

Diseases in the central nervous system (CNS) are often difficult to treat. Antibody- and protein-based therapeutics hold huge promises in CNS disease treatment. However, proteins are restricted from entering the CNS by the blood–brain barrier (BBB). To achieve enhanced BBB crossing, antibody-based c...

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Detalles Bibliográficos
Autores principales: Zhao, Peng, Zhang, Ningyan, An, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759110/
https://www.ncbi.nlm.nih.gov/pubmed/36540309
http://dx.doi.org/10.1093/abt/tbac028

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