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Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway

AIM: The aim of this study was to investigate the therapeutic roles of Tetrandrine (TET) on traumatic brain injury (TBI) and the underlying mechanism. METHOD: Traumatic injury model of hippocampal neurons and TBI mouse model were established to evaluate the therapeutic effects. The expression of neu...

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Detalles Bibliográficos
Autores principales: Liu, Huan, He, Shiqing, Li, Chong, Wang, Jianpeng, Zou, Qin, Liao, Yongshi, Chen, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759135/
https://www.ncbi.nlm.nih.gov/pubmed/36377337
http://dx.doi.org/10.1002/brb3.2786