Cargando…

Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway

AIM: The aim of this study was to investigate the therapeutic roles of Tetrandrine (TET) on traumatic brain injury (TBI) and the underlying mechanism. METHOD: Traumatic injury model of hippocampal neurons and TBI mouse model were established to evaluate the therapeutic effects. The expression of neu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Huan, He, Shiqing, Li, Chong, Wang, Jianpeng, Zou, Qin, Liao, Yongshi, Chen, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759135/ https://www.ncbi.nlm.nih.gov/pubmed/36377337 http://dx.doi.org/10.1002/brb3.2786

Ejemplares similares

eIF2α-CHOP-BCl-2/JNK and IRE1α-XBP1/JNK signaling promote apoptosis and inflammation and support the proliferation of Newcastle disease virus
por: Li, Yanrong, et al.
Publicado: (2019)

ROR2 induces cell apoptosis via activating IRE1α/JNK/CHOP pathway in high-grade serous ovarian carcinoma in vitro and in vivo
por: Li, Rui, et al.
Publicado: (2019)

Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways
por: Yi, Shanyong, et al.
Publicado: (2019)

Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells
por: Kim, Tae Woo, et al.
Publicado: (2018)

Tetrandrine Ameliorates Rheumatoid Arthritis in Mice by Alleviating Neutrophil Activities
por: Lu, Qingyi, et al.
Publicado: (2022)

Combination of Palmitic Acid and Methylseleninic Acid Induces Mitochondria-Dependent Apoptosis via Attenuation of the IRE1α Arm and Enhancement of CHOP in Hepatoma
por: Zhang, Han, et al.
Publicado: (2021)

Preliminary Study on the Effect and Molecular Mechanism of Tetrandrine in Alleviating Pulmonary Inflammation and Fibrosis Induced by Silicon Dioxide
por: Wang, Yi, et al.
Publicado: (2023)

Psoralen Inhibited Apoptosis of Osteoporotic Osteoblasts by Modulating IRE1-ASK1-JNK Pathway
por: Chen, Shuqing, et al.
Publicado: (2017)

Corosolic acid, a natural triterpenoid, induces ER stress-dependent apoptosis in human castration resistant prostate cancer cells via activation of IRE-1/JNK, PERK/CHOP and TRIB3
por: Ma, Bo, et al.
Publicado: (2018)

Effect of Different Exercise Intensities on Hepatocyte Apoptosis in HFD-Induced NAFLD in Rats: The Possible Role of Endoplasmic Reticulum Stress through the Regulation of the IRE1/JNK and eIF2α/CHOP Signal Pathways
por: Ruan, Ling, et al.
Publicado: (2021)

Dimethyl fumarate abrogates striatal endoplasmic reticulum stress in experimentally induced late-stage Huntington’s disease: Focus on the IRE1α/JNK and PERK/CHOP trajectories
por: Hassab, Lina Y., et al.
Publicado: (2023)

Inhibition of neutrophil extracellular trap formation ameliorates neuroinflammation and neuronal apoptosis via STING-dependent IRE1α/ASK1/JNK signaling pathway in mice with traumatic brain injury
por: Shi, Guihong, et al.
Publicado: (2023)

VceC Mediated IRE1 Pathway and Inhibited CHOP-induced Apoptosis to Support Brucella Replication in Goat Trophoblast Cells
por: Zhi, Feijie, et al.
Publicado: (2019)

Hydrogen (H(2)) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway
por: Lu, Hongwei, et al.
Publicado: (2021)

L-Ascorbic Acid Inhibits Breast Cancer Growth by Inducing IRE/JNK/CHOP-Related Endoplasmic Reticulum Stress-Mediated p62/SQSTM1 Accumulation in the Nucleus
por: Choi, Youn Kyung, et al.
Publicado: (2020)

Vanillin oxime inhibits lung cancer cell proliferation and activates apoptosis through JNK/ERK-CHOP pathway
por: Shen, Jie, et al.
Publicado: (2021)

Tetrandrine alleviates podocyte injury via calcium-dependent calpain-1 signaling blockade
por: Ding, Yin, et al.
Publicado: (2021)

Tetrandrine suppresses cervical cancer growth by inducing apoptosis in vitro and in vivo
por: Zhang, Haiyan, et al.
Publicado: (2018)

Emodin-Induced Oxidative Inhibition of Mitochondrial Function Assists BiP/IRE1α/CHOP Signaling-Mediated ER-Related Apoptosis
por: Qiu, Li-zhen, et al.
Publicado: (2021)

KDELR2 knockdown synergizes with temozolomide to induce glioma cell apoptosis through the CHOP and JNK/p38 pathways
por: Zhang, Guofeng, et al.
Publicado: (2021)

Tetrandrine attenuates ischemia/reperfusion-induced neuronal damage in the subacute phase
por: Wang, Yu, et al.
Publicado: (2021)

Melatonin promotes sirtuin 1 expression and inhibits IRE1α–XBP1S–CHOP to reduce endoplasmic reticulum stress–mediated apoptosis in chondrocytes
por: Qin, Kunpeng, et al.
Publicado: (2022)

Tetrandrine Inhibits the Wnt/β-Catenin Signalling Pathway and Alleviates Osteoarthritis: An In Vitro and In Vivo Study
por: Zhou, Xindie, et al.
Publicado: (2013)

Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP
por: Chen, L, et al.
Publicado: (2014)

Metformin Alleviated Aβ-Induced Apoptosis via the Suppression of JNK MAPK Signaling Pathway in Cultured Hippocampal Neurons
por: Chen, Bin, et al.
Publicado: (2016)

Silibinin alleviates intestinal inflammation via inhibiting JNK signaling in Drosophila
por: Yan, La, et al.
Publicado: (2023)

Exendin-4 Protects MIN6 Cells from t-BHP-Induced Apoptosis via IRE1-JNK-Caspase-3 Signaling
por: Chen, Wen-Jia, et al.
Publicado: (2012)

Tetrandrine alleviates silicosis by inhibiting canonical and non-canonical NLRP3 inflammasome activation in lung macrophages
por: Song, Mei-yue, et al.
Publicado: (2021)

JNK and Autophagy Independently Contributed to Cytotoxicity of Arsenite combined With Tetrandrine via Modulating Cell Cycle Progression in Human Breast Cancer Cells
por: Yu, Bowen, et al.
Publicado: (2020)

Tetrandrine blocks autophagic flux and induces apoptosis via energetic impairment in cancer cells
por: Qiu, W, et al.
Publicado: (2014)

Tetrandrine Induces Mitochondria-Mediated Apoptosis in Human Gastric Cancer BGC-823 Cells
por: Qin, Rong, et al.
Publicado: (2013)

Tetrandrine Derivatives as Promising Antibacterial Agents
por: Calvillo-Páez, Viviana I., et al.
Publicado: (2023)

Soluble epoxide hydrolase deficiency attenuates airway inflammation in COPD via IRE1α/JNK/AP-1 signaling pathway
por: Yu, Yue, et al.
Publicado: (2023)

High glucose and bupivacaine-induced cytotoxicity is mediated by enhanced apoptosis and impaired autophagy via the PERK-ATF4-CHOP and IRE1-TRAF2 signaling pathways
por: Liu, Yongzhe, et al.
Publicado: (2019)

Curcumin Sensitizes Kidney Cancer Cells to TRAIL-Induced Apoptosis via ROS Mediated Activation of JNK-CHOP Pathway and Upregulation of DR4
por: Obaidi, Ismael, et al.
Publicado: (2020)

Topical Application of Tetrandrine Nanoemulsion Promotes the Expansion of CD4(+)Foxp3(+) Regulatory T Cells and Alleviates Imiquimod-Induced Psoriasis in Mice
por: Chen, Shaokui, et al.
Publicado: (2022)

Tetrandrine alleviates cerebral ischemia/reperfusion injury by suppressing NLRP3 inflammasome activation via Sirt-1
por: Wang, Jun, et al.
Publicado: (2020)

Tetrandrine suppresses proliferation, induces apoptosis, and inhibits migration and invasion in human prostate cancer cells
por: Liu, Wei, et al.
Publicado: (2015)

JNK inhibitor alleviates apoptosis of fetal neural stem cells induced by emulsified isoflurane
por: Zhou, Lei, et al.
Publicado: (2017)

C/EBP homologous protein (CHOP) mediates neuronal apoptosis in rats with spinal cord injury
por: WANG, ZHANGFU, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_btssfv10jnr2loo23rq5jsbcb2