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COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2

INTRODUCTION: This review highlights the potential mechanisms of neuromuscular manifestation of COVID‐19, especially myasthenia gravis (MG). METHODS: An extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2...

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Autores principales: Shah, Syed Muhammad Ismail, Yasmin, Farah, Memon, Roha Saeed, Jatoi, Nadia Nazir, Savul, Ilma Saleh, Kazmi, Sana, Monawwer, Syed Abdullah, Zafar, Muhammad Daim Bin, Asghar, Muhammad Sohaib, Tahir, Muhammad Junaid, Lee, Ka Yiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759145/
https://www.ncbi.nlm.nih.gov/pubmed/36306401
http://dx.doi.org/10.1002/brb3.2789
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author Shah, Syed Muhammad Ismail
Yasmin, Farah
Memon, Roha Saeed
Jatoi, Nadia Nazir
Savul, Ilma Saleh
Kazmi, Sana
Monawwer, Syed Abdullah
Zafar, Muhammad Daim Bin
Asghar, Muhammad Sohaib
Tahir, Muhammad Junaid
Lee, Ka Yiu
author_facet Shah, Syed Muhammad Ismail
Yasmin, Farah
Memon, Roha Saeed
Jatoi, Nadia Nazir
Savul, Ilma Saleh
Kazmi, Sana
Monawwer, Syed Abdullah
Zafar, Muhammad Daim Bin
Asghar, Muhammad Sohaib
Tahir, Muhammad Junaid
Lee, Ka Yiu
author_sort Shah, Syed Muhammad Ismail
collection PubMed
description INTRODUCTION: This review highlights the potential mechanisms of neuromuscular manifestation of COVID‐19, especially myasthenia gravis (MG). METHODS: An extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2020. RESULTS: Exacerbations of clinical symptoms in patients of MG who were treated with some commonly used COVID‐19 drugs has been reported, with updated recommendations of management of symptoms of neuromuscular disorders. Severe acute respiratory syndrome coronavirus 2 can induce the immune response to trigger autoimmune neurological disorders. CONCLUSIONS: Further clinical studies are warranted to indicate and rather confirm if MG in the setting of COVID‐19 can pre‐existent subclinically or develop as a new‐onset disease.
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spelling pubmed-97591452022-12-20 COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2 Shah, Syed Muhammad Ismail Yasmin, Farah Memon, Roha Saeed Jatoi, Nadia Nazir Savul, Ilma Saleh Kazmi, Sana Monawwer, Syed Abdullah Zafar, Muhammad Daim Bin Asghar, Muhammad Sohaib Tahir, Muhammad Junaid Lee, Ka Yiu Brain Behav Reviews INTRODUCTION: This review highlights the potential mechanisms of neuromuscular manifestation of COVID‐19, especially myasthenia gravis (MG). METHODS: An extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2020. RESULTS: Exacerbations of clinical symptoms in patients of MG who were treated with some commonly used COVID‐19 drugs has been reported, with updated recommendations of management of symptoms of neuromuscular disorders. Severe acute respiratory syndrome coronavirus 2 can induce the immune response to trigger autoimmune neurological disorders. CONCLUSIONS: Further clinical studies are warranted to indicate and rather confirm if MG in the setting of COVID‐19 can pre‐existent subclinically or develop as a new‐onset disease. John Wiley and Sons Inc. 2022-10-28 /pmc/articles/PMC9759145/ /pubmed/36306401 http://dx.doi.org/10.1002/brb3.2789 Text en © 2022 The Authors. Brain and Behavior published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Shah, Syed Muhammad Ismail
Yasmin, Farah
Memon, Roha Saeed
Jatoi, Nadia Nazir
Savul, Ilma Saleh
Kazmi, Sana
Monawwer, Syed Abdullah
Zafar, Muhammad Daim Bin
Asghar, Muhammad Sohaib
Tahir, Muhammad Junaid
Lee, Ka Yiu
COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
title COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
title_full COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
title_fullStr COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
title_full_unstemmed COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
title_short COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
title_sort covid‐19 and myasthenia gravis: a review of neurological implications of the sars‐cov‐2
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759145/
https://www.ncbi.nlm.nih.gov/pubmed/36306401
http://dx.doi.org/10.1002/brb3.2789
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