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Evidence supporting the use of a brief cognitive assessment in routine clinical assessment for psychosis

Cognitive impairment is a core feature of psychosis. Full cognitive assessments are not often conducted in routine clinical practice as administration is time-consuming. Here, we investigated whether brief tests of cognition could be used to predict broader neurocognitive performance in a manner pra...

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Autores principales: Cowman, M., Lonergan, E., Burke, T., Bowie, C. R., Corvin, A., Morris, D. W., O’Connor, K., Donohoe, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759520/
https://www.ncbi.nlm.nih.gov/pubmed/36528607
http://dx.doi.org/10.1038/s41537-022-00322-z
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author Cowman, M.
Lonergan, E.
Burke, T.
Bowie, C. R.
Corvin, A.
Morris, D. W.
O’Connor, K.
Donohoe, G.
author_facet Cowman, M.
Lonergan, E.
Burke, T.
Bowie, C. R.
Corvin, A.
Morris, D. W.
O’Connor, K.
Donohoe, G.
author_sort Cowman, M.
collection PubMed
description Cognitive impairment is a core feature of psychosis. Full cognitive assessments are not often conducted in routine clinical practice as administration is time-consuming. Here, we investigated whether brief tests of cognition could be used to predict broader neurocognitive performance in a manner practical for screening use in mental health services. We carried out a principal component analysis (PCA) to obtain an estimate of general cognitive function (N = 415). We investigated whether brief tests of memory accounted for a significant percentage of variation in the PCA scores. We used discriminant function analysis to determine if measures could predict classification as lower, intermediate or higher level of cognitive function and to what extent these groups overlapped with groups based on normative data. Memory tests correctly classified 65% of cases in the highest scoring group, 35% of cases in the intermediate group, and 77% of cases in the lowest scoring group. These PCA-derived groups and groups based on normative scores for the two tests were significantly associated (χ2 = 164.00, p < 0.001). These measures accurately identified three quarters of the low performing group, the group of greatest interest from the perspective of identifying those likely to need greater supports as part of clinical care. In so doing they suggest a potentially useful approach to screening for cognitive impairment in clinical services, upon which further assessment can be built if required.
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spelling pubmed-97595202022-12-19 Evidence supporting the use of a brief cognitive assessment in routine clinical assessment for psychosis Cowman, M. Lonergan, E. Burke, T. Bowie, C. R. Corvin, A. Morris, D. W. O’Connor, K. Donohoe, G. Schizophrenia (Heidelb) Article Cognitive impairment is a core feature of psychosis. Full cognitive assessments are not often conducted in routine clinical practice as administration is time-consuming. Here, we investigated whether brief tests of cognition could be used to predict broader neurocognitive performance in a manner practical for screening use in mental health services. We carried out a principal component analysis (PCA) to obtain an estimate of general cognitive function (N = 415). We investigated whether brief tests of memory accounted for a significant percentage of variation in the PCA scores. We used discriminant function analysis to determine if measures could predict classification as lower, intermediate or higher level of cognitive function and to what extent these groups overlapped with groups based on normative data. Memory tests correctly classified 65% of cases in the highest scoring group, 35% of cases in the intermediate group, and 77% of cases in the lowest scoring group. These PCA-derived groups and groups based on normative scores for the two tests were significantly associated (χ2 = 164.00, p < 0.001). These measures accurately identified three quarters of the low performing group, the group of greatest interest from the perspective of identifying those likely to need greater supports as part of clinical care. In so doing they suggest a potentially useful approach to screening for cognitive impairment in clinical services, upon which further assessment can be built if required. Nature Publishing Group UK 2022-12-17 /pmc/articles/PMC9759520/ /pubmed/36528607 http://dx.doi.org/10.1038/s41537-022-00322-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Cowman, M.
Lonergan, E.
Burke, T.
Bowie, C. R.
Corvin, A.
Morris, D. W.
O’Connor, K.
Donohoe, G.
Evidence supporting the use of a brief cognitive assessment in routine clinical assessment for psychosis
title Evidence supporting the use of a brief cognitive assessment in routine clinical assessment for psychosis
title_full Evidence supporting the use of a brief cognitive assessment in routine clinical assessment for psychosis
title_fullStr Evidence supporting the use of a brief cognitive assessment in routine clinical assessment for psychosis
title_full_unstemmed Evidence supporting the use of a brief cognitive assessment in routine clinical assessment for psychosis
title_short Evidence supporting the use of a brief cognitive assessment in routine clinical assessment for psychosis
title_sort evidence supporting the use of a brief cognitive assessment in routine clinical assessment for psychosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759520/
https://www.ncbi.nlm.nih.gov/pubmed/36528607
http://dx.doi.org/10.1038/s41537-022-00322-z
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