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Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism

Little is known about the impact of morphological disorders in distinct zones on metabolic zonation. It was described recently that periportal fibrosis did affect the expression of CYP proteins, a set of pericentrally located drug-metabolizing enzymes. Here, we investigated whether periportal steato...

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Detalles Bibliográficos
Autores principales: Albadry, Mohamed, Höpfl, Sebastian, Ehteshamzad, Nadia, König, Matthias, Böttcher, Michael, Neumann, Jasna, Lupp, Amelie, Dirsch, Olaf, Radde, Nicole, Christ, Bruno, Christ, Madlen, Schwen, Lars Ole, Laue, Hendrik, Klopfleisch, Robert, Dahmen, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759570/
https://www.ncbi.nlm.nih.gov/pubmed/36528753
http://dx.doi.org/10.1038/s41598-022-26483-6