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Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism
Little is known about the impact of morphological disorders in distinct zones on metabolic zonation. It was described recently that periportal fibrosis did affect the expression of CYP proteins, a set of pericentrally located drug-metabolizing enzymes. Here, we investigated whether periportal steato...
Autores principales: | Albadry, Mohamed, Höpfl, Sebastian, Ehteshamzad, Nadia, König, Matthias, Böttcher, Michael, Neumann, Jasna, Lupp, Amelie, Dirsch, Olaf, Radde, Nicole, Christ, Bruno, Christ, Madlen, Schwen, Lars Ole, Laue, Hendrik, Klopfleisch, Robert, Dahmen, Uta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759570/ https://www.ncbi.nlm.nih.gov/pubmed/36528753 http://dx.doi.org/10.1038/s41598-022-26483-6 |
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