Cargando…

PSMC3 promotes RNAi by maintaining AGO2 stability through USP14

BACKGROUND: Argonaute 2 (AGO2), the only protein with catalytic activity in the human Argonaute family, is considered as a key component of RNA interference (RNAi) pathway. Here we performed a yeast two-hybrid screen using the human Argonaute 2 PIWI domain as bait to screen for new AGO2-interacting...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Yan, Zhao, Jianing, Yu, Tao, Zhang, Xue, Qi, Xiaozhen, Hao, Tongxin, Jin, Zeyuan, Zhao, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759854/
https://www.ncbi.nlm.nih.gov/pubmed/36528617
http://dx.doi.org/10.1186/s11658-022-00411-y