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Saturated very long-chain fatty acids regulate macrophage plasticity and invasiveness

Saturated very long-chain fatty acids (VLCFA, ≥ C22), enriched in brain myelin and innate immune cells, accumulate in X-linked adrenoleukodystrophy (X-ALD) due to inherited dysfunction of the peroxisomal VLCFA transporter ABCD1. In its severest form, X-ALD causes cerebral myelin destruction with inf...

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Detalles Bibliográficos
Autores principales:	Zierfuss, Bettina, Buda, Agnieszka, Villoria-González, Andrea, Logist, Maxime, Fabjan, Jure, Parzer, Patricia, Battin, Claire, Vandersteene, Streggi, Dijkstra, Inge M. E., Waidhofer-Söllner, Petra, Grabmeier-Pfistershammer, Katharina, Steinberger, Peter, Kemp, Stephan, Forss-Petter, Sonja, Berger, Johannes, Weinhofer, Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759912/ https://www.ncbi.nlm.nih.gov/pubmed/36528616 http://dx.doi.org/10.1186/s12974-022-02664-y

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