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A case of Takayasu arteritis complicated with pulmonary infarction

Takayasu arteritis (TAK) is a vasculitis that causes inflammation in the arterial walls of large blood vessels. The complication rate of pulmonary artery lesion in TAK has been reported to be relatively high. Severe pulmonary artery stenosis can cause pulmonary infarction in rare cases. A 48-year-ol...

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Autores principales: Hirayama, Takehiro, Morita, Takayoshi, Funakoshi, Kenji, Yoshimine, Yuko, Minoda, Saki, Murakami, Teruaki, Okita, Yasutaka, Narazaki, Masashi, Kumanogoh, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759950/
https://www.ncbi.nlm.nih.gov/pubmed/36540845
http://dx.doi.org/10.1093/omcr/omac140
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author Hirayama, Takehiro
Morita, Takayoshi
Funakoshi, Kenji
Yoshimine, Yuko
Minoda, Saki
Murakami, Teruaki
Okita, Yasutaka
Narazaki, Masashi
Kumanogoh, Atsushi
author_facet Hirayama, Takehiro
Morita, Takayoshi
Funakoshi, Kenji
Yoshimine, Yuko
Minoda, Saki
Murakami, Teruaki
Okita, Yasutaka
Narazaki, Masashi
Kumanogoh, Atsushi
author_sort Hirayama, Takehiro
collection PubMed
description Takayasu arteritis (TAK) is a vasculitis that causes inflammation in the arterial walls of large blood vessels. The complication rate of pulmonary artery lesion in TAK has been reported to be relatively high. Severe pulmonary artery stenosis can cause pulmonary infarction in rare cases. A 48-year-old woman had experienced cough and fever persistently for 3 months and visited a city hospital. Contrast-enhanced computed tomography (CT) and positron emission tomography (PET)-CT scans revealed TAK complicated with left pulmonary artery lesion. Contrast-enhanced CT couldn’t detect wall thickening in the left smaller bifurcated pulmonary artery branch, but PET-CT did reveal this inflammation. Several weeks after we initiated treatment with high-dose prednisolone, the patient’s symptoms and inflammatory findings disappeared. PET-CT may be useful for evaluating the inflammation of the pulmonary artery in TAK, and high-dose steroid monotherapy as induction therapy may be effective for TAK complicated with pulmonary artery lesions causing pulmonary infarction.
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spelling pubmed-97599502022-12-19 A case of Takayasu arteritis complicated with pulmonary infarction Hirayama, Takehiro Morita, Takayoshi Funakoshi, Kenji Yoshimine, Yuko Minoda, Saki Murakami, Teruaki Okita, Yasutaka Narazaki, Masashi Kumanogoh, Atsushi Oxf Med Case Reports Case Report Takayasu arteritis (TAK) is a vasculitis that causes inflammation in the arterial walls of large blood vessels. The complication rate of pulmonary artery lesion in TAK has been reported to be relatively high. Severe pulmonary artery stenosis can cause pulmonary infarction in rare cases. A 48-year-old woman had experienced cough and fever persistently for 3 months and visited a city hospital. Contrast-enhanced computed tomography (CT) and positron emission tomography (PET)-CT scans revealed TAK complicated with left pulmonary artery lesion. Contrast-enhanced CT couldn’t detect wall thickening in the left smaller bifurcated pulmonary artery branch, but PET-CT did reveal this inflammation. Several weeks after we initiated treatment with high-dose prednisolone, the patient’s symptoms and inflammatory findings disappeared. PET-CT may be useful for evaluating the inflammation of the pulmonary artery in TAK, and high-dose steroid monotherapy as induction therapy may be effective for TAK complicated with pulmonary artery lesions causing pulmonary infarction. Oxford University Press 2022-12-16 /pmc/articles/PMC9759950/ /pubmed/36540845 http://dx.doi.org/10.1093/omcr/omac140 Text en © The Author(s) 2022. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Hirayama, Takehiro
Morita, Takayoshi
Funakoshi, Kenji
Yoshimine, Yuko
Minoda, Saki
Murakami, Teruaki
Okita, Yasutaka
Narazaki, Masashi
Kumanogoh, Atsushi
A case of Takayasu arteritis complicated with pulmonary infarction
title A case of Takayasu arteritis complicated with pulmonary infarction
title_full A case of Takayasu arteritis complicated with pulmonary infarction
title_fullStr A case of Takayasu arteritis complicated with pulmonary infarction
title_full_unstemmed A case of Takayasu arteritis complicated with pulmonary infarction
title_short A case of Takayasu arteritis complicated with pulmonary infarction
title_sort case of takayasu arteritis complicated with pulmonary infarction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759950/
https://www.ncbi.nlm.nih.gov/pubmed/36540845
http://dx.doi.org/10.1093/omcr/omac140
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