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A stapled chromogranin A-derived peptide homes in on tumors that express αvβ6 or αvβ8 integrins

Rationale: The αvβ6- and αvβ8-integrins, two cell-adhesion receptors upregulated in many tumors and involved in the activation of the latency associated peptide (LAP)/TGFβ complex, represent potential targets for tumor imaging and therapy. We investigated the tumor-homing properties of a chromograni...

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Detalles Bibliográficos
Autores principales: Monieri, Matteo, Rainone, Paolo, Sacchi, Angelina, Gori, Alessandro, Gasparri, Anna Maria, Coliva, Angela, Citro, Antonio, Ferrara, Benedetta, Policardi, Martina, Valtorta, Silvia, Pocaterra, Arianna, Alfano, Massimo, Sheppard, Dean, Piemonti, Lorenzo, Moresco, Rosa Maria, Corti, Angelo, Curnis, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760430/
https://www.ncbi.nlm.nih.gov/pubmed/36594095
http://dx.doi.org/10.7150/ijbs.76148