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N-glycosylation-mediated CD147 accumulation induces cardiac fibrosis in the diabetic heart through ALK5 activation

Emerging evidence has implicated the important role of fibrosis in diabetic cardiomyopathy (DCM), while the underlying mechanism remains unclear. Considering the distinct and overlapping roles of Cluster of Differentiation 147 (CD147) in the pathogenesis of fibrotic diseases, we aim to investigate t...

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Detalles Bibliográficos
Autores principales: Liu, Mingchuan, Peng, Tingwei, Hu, Lang, Wang, Min, Guo, Dong, Qi, Bingchao, Ren, Gaotong, Wang, Di, Li, Yunqing, Song, Liqiang, Hu, Jianqiang, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760447/
https://www.ncbi.nlm.nih.gov/pubmed/36594096
http://dx.doi.org/10.7150/ijbs.77469