The role of thalamic group II mGlu receptors in health and disease

The thalamus plays a pivotal role in the integration and processing of sensory, motor, and cognitive information. It is therefore important to understand how the thalamus operates in states of both health and disease. In the present review, we discuss the function of the Group II metabotropic glutam...

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Detalles Bibliográficos
Autores principales: Copeland, Caroline S., Salt, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Molecular Bases of Health & Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760452/
https://www.ncbi.nlm.nih.gov/pubmed/36561092
http://dx.doi.org/10.1042/NS20210058
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author Copeland, Caroline S.
Salt, Thomas E.
author_facet Copeland, Caroline S.
Salt, Thomas E.
author_sort Copeland, Caroline S.
collection PubMed
description The thalamus plays a pivotal role in the integration and processing of sensory, motor, and cognitive information. It is therefore important to understand how the thalamus operates in states of both health and disease. In the present review, we discuss the function of the Group II metabotropic glutamate (mGlu) receptors within thalamic circuitry, and how they may represent therapeutic targets in treating disease states associated with thalamic dysfunction.
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spelling pubmed-97604522022-12-21 The role of thalamic group II mGlu receptors in health and disease Copeland, Caroline S. Salt, Thomas E. Neuronal Signal Molecular Bases of Health & Disease The thalamus plays a pivotal role in the integration and processing of sensory, motor, and cognitive information. It is therefore important to understand how the thalamus operates in states of both health and disease. In the present review, we discuss the function of the Group II metabotropic glutamate (mGlu) receptors within thalamic circuitry, and how they may represent therapeutic targets in treating disease states associated with thalamic dysfunction. Portland Press Ltd. 2022-11-15 /pmc/articles/PMC9760452/ /pubmed/36561092 http://dx.doi.org/10.1042/NS20210058 Text en © 2022 The Author(s). https://creativecommons.org/licenses/by/4.0/This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) (https://creativecommons.org/licenses/by/4.0/) . Open access for the present article was enabled by the participation of University College London in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with JISC.
spellingShingle Molecular Bases of Health & Disease
Copeland, Caroline S.
Salt, Thomas E.
The role of thalamic group II mGlu receptors in health and disease
title The role of thalamic group II mGlu receptors in health and disease
title_full The role of thalamic group II mGlu receptors in health and disease
title_fullStr The role of thalamic group II mGlu receptors in health and disease
title_full_unstemmed The role of thalamic group II mGlu receptors in health and disease
title_short The role of thalamic group II mGlu receptors in health and disease
title_sort role of thalamic group ii mglu receptors in health and disease
topic Molecular Bases of Health & Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760452/
https://www.ncbi.nlm.nih.gov/pubmed/36561092
http://dx.doi.org/10.1042/NS20210058
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