Cargando…

Immunomodulatory Cell Therapy Using αGalCer-Pulsed Dendritic Cells Ameliorates Heart Failure in a Murine Dilated Cardiomyopathy Model

Dilated cardiomyopathy (DCM) is a life-threatening disease, resulting in refractory heart failure. An immune disorder underlies the pathophysiology associated with heart failure progression. Invariant natural killer T (iNKT) cell activation is a prospective therapeutic strategy for ischemic heart di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ikeda, Masataka, Ide, Tomomi, Matsushima, Shouji, Ikeda, Soichiro, Okabe, Kosuke, Ishikita, Akihito, Tadokoro, Tomonori, Sada, Masashi, Abe, Ko, Sato, Midori, Hanada, Akiko, Arai, Shinobu, Ohtani, Kisho, Nonami, Atsushi, Mizuno, Shinichi, Morimoto, Sachio, Motohashi, Shinichiro, Akashi, Koichi, Taniguchi, Masaru, Tsutsui, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760469/ https://www.ncbi.nlm.nih.gov/pubmed/36268712 http://dx.doi.org/10.1161/CIRCHEARTFAILURE.122.009366

Ejemplares similares

Synthesis of a 2''-Deoxy-β-GalCer
por: Thakur, Meena S., et al.
Publicado: (2014)

Blockade of L-type Ca(2+) channel attenuates doxorubicin-induced cardiomyopathy via suppression of CaMKII-NF-κB pathway
por: Ikeda, Soichiro, et al.
Publicado: (2019)

A Multifactorial Mechanism in the Superior Antimalarial Activity of α-C-GalCer
por: Schmieg, John, et al.
Publicado: (2010)

Interaction between Bacteria and the Immune System for Cancer Immunotherapy: The α-GalCer Alliance
por: Ustjanzew, Arsenij, et al.
Publicado: (2022)

α-GalCer and iNKT Cell-Based Cancer Immunotherapy: Realizing the Therapeutic Potentials
por: Zhang, Yingting, et al.
Publicado: (2019)

Galactosylsphingamides: new α-GalCer analogues to probe the F’-pocket of CD1d
por: Guillaume, Joren, et al.
Publicado: (2017)

Excessive Hypoxia‐Inducible Factor‐1α Expression Induces Cardiac Rupture via p53‐Dependent Apoptosis After Myocardial Infarction
por: Ikeda, Masataka, et al.
Publicado: (2021)

6″-Modifed α-GalCer-peptide conjugate vaccine candidates protect against liver-stage malaria
por: Meijlink, Michael A., et al.
Publicado: (2022)

Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity
por: Tadokoro, Tomonori, et al.
Publicado: (2023)

IFN-γ-STAT1-ERK Pathway Mediates Protective Effects of Invariant Natural Killer T Cells Against Doxorubicin-Induced Cardiomyocyte Death
por: Sada, Masashi, et al.
Publicado: (2023)

Modulation of NKT cells and Th1/Th2 imbalance after α-GalCer treatment in progressive load-trained rats
por: Ru, Wang, et al.
Publicado: (2009)

Thermodynamic and Structural Behavior of α‐Galactosylceramide and C6‐Functionalized α‐GalCer in 2D Layers at the Air–Liquid Interface
por: Brezesinski, Gerald, et al.
Publicado: (2019)

Encapsulation of MERS antigen into α-GalCer-bearing-liposomes elicits stronger effector and memory immune responses in immunocompetent and leukopenic mice
por: Khan, Masood Alam, et al.
Publicado: (2022)

Tumor-Localized Administration of α-GalCer to Recruit Invariant Natural Killer T Cells and Enhance Their Antitumor Activity against Solid Tumors
por: Li, Yan-Ruide, et al.
Publicado: (2022)

ZBP1 Protects Against mtDNA-Induced Myocardial Inflammation in Failing Hearts
por: Enzan, Nobuyuki, et al.
Publicado: (2023)

A Glycolipid α-GalCer Derivative, 7DW8-5 as a Novel Mucosal Adjuvant for the Split Inactivated Influenza Vaccine
por: Feng, Huapeng, et al.
Publicado: (2022)

Left Ventricular Noncompaction with Multiple Thrombi in Apical Aneurysm
por: Yakabe, Daisuke, et al.
Publicado: (2019)

Immune Modulating Effects of NKT Cells in a Physiologically Low Dose Leishmania major Infection Model after αGalCer Analog PBS57 Stimulation
por: Griewank, Klaus G., et al.
Publicado: (2014)

Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A’ Pocket Unable to Bind Long-Chain Glycolipids
por: Wang, Jing, et al.
Publicado: (2012)

A Designed α‐GalCer Analog Promotes Considerable Th1 Cytokine Response by Activating the CD1d‐iNKT Axis and CD11b‐Positive Monocytes/Macrophages
por: Ma, Juan, et al.
Publicado: (2020)

Repeated α-GalCer Administration Induces a Type 2 Cytokine-Biased iNKT Cell Response and Exacerbates Atopic Skin Inflammation in Vα14(Tg) NC/Nga Mice
por: Park, Hyun Jung, et al.
Publicado: (2021)

Visibility of Pulmonary Valve and Pulmonary Regurgitation on Intracardiac Echocardiography in Adult Patients with Tetralogy of Fallot
por: Sakamoto, Ichiro, et al.
Publicado: (2023)

Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury
por: Miyamoto, Hiroko Deguchi, et al.
Publicado: (2022)

A randomized phase II study to assess the effect of adjuvant immunotherapy using α-GalCer-pulsed dendritic cells in the patients with completely resected stage II–IIIA non-small cell lung cancer: study protocol for a randomized controlled trial
por: Saka, Hideo, et al.
Publicado: (2017)

Long-Term Outcomes of Heart Failure Patients With Preserved, Mildly Reduced, and Reduced Ejection Fraction
por: Nagata, Takuya, et al.
Publicado: (2023)

Machine learning‐based model for predicting 1 year mortality of hospitalized patients with heart failure
por: Tohyama, Takeshi, et al.
Publicado: (2021)

Fulminant necrotizing eosinophilic myocarditis after COVID‐19 vaccination survived with mechanical circulatory support
por: Kimura, Mitsukuni, et al.
Publicado: (2022)

The use of angiotensin II receptor blocker is associated with greater recovery of cardiac function than angiotensin‐converting enzyme inhibitor in dilated cardiomyopathy
por: Enzan, Nobuyuki, et al.
Publicado: (2022)

Beneficial Effects of Dipeptidyl Peptidase-4 Inhibitors on Heart Failure With Preserved Ejection Fraction and Diabetes
por: Enzan, Nobuyuki, et al.
Publicado: (2023)

Comparative Effectiveness Research (CER): A Summary of AHRQ’s CER on Therapies for Rheumatoid Arthritis
por: Oderda, Gary M., et al.
Publicado: (2011)

Spironolactone use is associated with improved outcomes in heart failure with mid‐range ejection fraction
por: Enzan, Nobuyuki, et al.
Publicado: (2020)

Electrocardiographic Left Ventricular Hypertrophy Is Independently Associated With Better Long-Term Outcomes in Dilated Cardiomyopathy Patients
por: Matsushima, Shouji, et al.
Publicado: (2019)

Implementing CER: What Will It Take?
por: Biskupiak, Joseph E., et al.
Publicado: (2012)

Clinical Characteristics and Contemporary Management of Patients With Cardiomyopathies in Japan　― Report From a National Registry of Clinical Personal Records ―
por: Enzan, Nobuyuki, et al.
Publicado: (2021)

Sex Differences in Time-Dependent Changes in B-Type Natriuretic Peptide in Hypertrophic Cardiomyopathy
por: Enzan, Nobuyuki, et al.
Publicado: (2021)

Beta‐Blocker Use Is Associated With Prevention of Left Ventricular Remodeling in Recovered Dilated Cardiomyopathy
por: Enzan, Nobuyuki, et al.
Publicado: (2021)

CerS1 but Not CerS5 Gene Silencing, Improves Insulin Sensitivity and Glucose Uptake in Skeletal Muscle
por: Błachnio-Zabielska, Agnieszka U., et al.
Publicado: (2022)

Oxidative stress in cardiac and skeletal muscle dysfunction associated with diabetes mellitus
por: Tsutsui, Hiroyuki, et al.
Publicado: (2011)

Patient engagement – the PaCER model
por: Hylton, Chris
Publicado: (2015)

Non-clinical development of CER-001
por: Barbaras, Ronald
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_uj3cacam8pu7mkbk48v69dd9h2