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Purvalanol A induces apoptosis and reverses cisplatin resistance in ovarian cancer

Cisplatin (DDP) resistance limits therapeutic efficacy in patients diagnosed with ovarian cancer. Purvalanol A (Pur) is a novel cyclin-dependent kinase (CDK) inhibitor that has been demonstrated to induce apoptosis in various cancer cells. The present study investigated the effect of the combination...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyi, Hong, Shasha, Yang, Jiang, Liu, Jingchun, Wang, Ying, Peng, Jiaxin, Wang, Haoyu, Hong, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760476/
https://www.ncbi.nlm.nih.gov/pubmed/35946506
http://dx.doi.org/10.1097/CAD.0000000000001339