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Electroacupuncture and acupuncture in the treatment of anxiety - A double blinded randomized parallel clinical trial
BACKGROUND: The estimated number of people living with anxiety disorders worldwide is around 264 million and is estimated to have worsened with the recent pandemic of COVID-19. Acupuncture has shown to have excellent therapeutic effects in reducing anxiety. DESIGN: Double-blinded randomized controll...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760487/ https://www.ncbi.nlm.nih.gov/pubmed/35124475 http://dx.doi.org/10.1016/j.ctcp.2022.101541 |
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author | Amorim, Diogo Brito, Irma Caseiro, Armando Figueiredo, João Paulo Pinto, André Macedo, Inês Machado, Jorge |
author_facet | Amorim, Diogo Brito, Irma Caseiro, Armando Figueiredo, João Paulo Pinto, André Macedo, Inês Machado, Jorge |
author_sort | Amorim, Diogo |
collection | PubMed |
description | BACKGROUND: The estimated number of people living with anxiety disorders worldwide is around 264 million and is estimated to have worsened with the recent pandemic of COVID-19. Acupuncture has shown to have excellent therapeutic effects in reducing anxiety. DESIGN: Double-blinded randomized controlled clinical trial with 56 participants (21–82 years) with anxiety diagnosed by 3 different anxiety scales (BAI, GAD-7 and OASIS). A 30-min acupuncture session was applied once a week for 10 weeks. AIMS: Evaluate the effectiveness of acupuncture and electroacupuncture in the treatment of anxiety to verify if: (1) People with high anxiety report reduced scores after 5 and 10 sessions; (2) Salivary cortisol levels accompanied the reduced scores; (3) Electroacupuncture treatment is more effective than acupuncture; (4) the treatments is independent of anxiolytic medication. METHODS: Volunteers were randomized into 3 groups (control, acupuncture, and electroacupuncture). The results were analyzed by anxiety scales and salivary cortisol tests. RESULTS: The findings show an improvement in anxiety, assessed by BAI, GAD-7 and OASIS, after the 5th session of acupuncture (p < 0.05) and electroacupuncture (p < 0.05) and the 10th session for both techniques (p < 0.001). The salivary cortisol values measured in the morning followed this pattern (p < 0.05), although the reduction of the night cortisol values was not statistically significant. Electroacupuncture and acupuncture show similar efficacy. The positive effect after the treatments is independent of anxiolytic medication (p < 0.001). CONCLUSION: Acupuncture and electroacupuncture are effective in treating anxiety on their own or as adjuncts to pharmacological therapy. TRIAL REGISTRATION NUMBER: NºP445-08/2017 (Unidade de Investigação em Ciências da Saúde); |
format | Online Article Text |
id | pubmed-9760487 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97604872022-12-19 Electroacupuncture and acupuncture in the treatment of anxiety - A double blinded randomized parallel clinical trial Amorim, Diogo Brito, Irma Caseiro, Armando Figueiredo, João Paulo Pinto, André Macedo, Inês Machado, Jorge Complement Ther Clin Pract Article BACKGROUND: The estimated number of people living with anxiety disorders worldwide is around 264 million and is estimated to have worsened with the recent pandemic of COVID-19. Acupuncture has shown to have excellent therapeutic effects in reducing anxiety. DESIGN: Double-blinded randomized controlled clinical trial with 56 participants (21–82 years) with anxiety diagnosed by 3 different anxiety scales (BAI, GAD-7 and OASIS). A 30-min acupuncture session was applied once a week for 10 weeks. AIMS: Evaluate the effectiveness of acupuncture and electroacupuncture in the treatment of anxiety to verify if: (1) People with high anxiety report reduced scores after 5 and 10 sessions; (2) Salivary cortisol levels accompanied the reduced scores; (3) Electroacupuncture treatment is more effective than acupuncture; (4) the treatments is independent of anxiolytic medication. METHODS: Volunteers were randomized into 3 groups (control, acupuncture, and electroacupuncture). The results were analyzed by anxiety scales and salivary cortisol tests. RESULTS: The findings show an improvement in anxiety, assessed by BAI, GAD-7 and OASIS, after the 5th session of acupuncture (p < 0.05) and electroacupuncture (p < 0.05) and the 10th session for both techniques (p < 0.001). The salivary cortisol values measured in the morning followed this pattern (p < 0.05), although the reduction of the night cortisol values was not statistically significant. Electroacupuncture and acupuncture show similar efficacy. The positive effect after the treatments is independent of anxiolytic medication (p < 0.001). CONCLUSION: Acupuncture and electroacupuncture are effective in treating anxiety on their own or as adjuncts to pharmacological therapy. TRIAL REGISTRATION NUMBER: NºP445-08/2017 (Unidade de Investigação em Ciências da Saúde); Published by Elsevier Ltd. 2022-02 2022-01-30 /pmc/articles/PMC9760487/ /pubmed/35124475 http://dx.doi.org/10.1016/j.ctcp.2022.101541 Text en © 2022 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Amorim, Diogo Brito, Irma Caseiro, Armando Figueiredo, João Paulo Pinto, André Macedo, Inês Machado, Jorge Electroacupuncture and acupuncture in the treatment of anxiety - A double blinded randomized parallel clinical trial |
title | Electroacupuncture and acupuncture in the treatment of anxiety - A double blinded randomized parallel clinical trial |
title_full | Electroacupuncture and acupuncture in the treatment of anxiety - A double blinded randomized parallel clinical trial |
title_fullStr | Electroacupuncture and acupuncture in the treatment of anxiety - A double blinded randomized parallel clinical trial |
title_full_unstemmed | Electroacupuncture and acupuncture in the treatment of anxiety - A double blinded randomized parallel clinical trial |
title_short | Electroacupuncture and acupuncture in the treatment of anxiety - A double blinded randomized parallel clinical trial |
title_sort | electroacupuncture and acupuncture in the treatment of anxiety - a double blinded randomized parallel clinical trial |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760487/ https://www.ncbi.nlm.nih.gov/pubmed/35124475 http://dx.doi.org/10.1016/j.ctcp.2022.101541 |
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