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Analogous comparison unravels heightened antiviral defense and boosted viral infection upon immunosuppression in bat organoids

Horseshoe bats host numerous SARS-related coronaviruses without overt disease signs. Bat intestinal organoids, a unique model of bat intestinal epithelium, allow direct comparison with human intestinal organoids. We sought to unravel the cellular mechanism(s) underlying bat tolerance of coronaviruse...

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Detalles Bibliográficos
Autores principales:	Liu, Xiaojuan, Li, Cun, Wan, Zhixin, Chiu, Man Chun, Huang, Jingjing, Yu, Yifei, Zhu, Lin, Cai, Jian-Piao, Rong, Lei, Song, You-qiang, Chu, Hin, Cai, Zongwei, Jiang, Shibo, Yuen, Kwok-yung, Zhou, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760641/ https://www.ncbi.nlm.nih.gov/pubmed/36529763 http://dx.doi.org/10.1038/s41392-022-01247-w

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