Cargando…

Analogous comparison unravels heightened antiviral defense and boosted viral infection upon immunosuppression in bat organoids

Horseshoe bats host numerous SARS-related coronaviruses without overt disease signs. Bat intestinal organoids, a unique model of bat intestinal epithelium, allow direct comparison with human intestinal organoids. We sought to unravel the cellular mechanism(s) underlying bat tolerance of coronaviruse...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xiaojuan, Li, Cun, Wan, Zhixin, Chiu, Man Chun, Huang, Jingjing, Yu, Yifei, Zhu, Lin, Cai, Jian-Piao, Rong, Lei, Song, You-qiang, Chu, Hin, Cai, Zongwei, Jiang, Shibo, Yuen, Kwok-yung, Zhou, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760641/ https://www.ncbi.nlm.nih.gov/pubmed/36529763 http://dx.doi.org/10.1038/s41392-022-01247-w

Ejemplares similares

Human Nasal Organoids Model SARS-CoV-2 Upper Respiratory Infection and Recapitulate the Differential Infectivity of Emerging Variants
por: Chiu, Man Chun, et al.
Publicado: (2022)

Human airway and nasal organoids reveal escalating replicative fitness of SARS-CoV-2 emerging variants
por: Li, Cun, et al.
Publicado: (2023)

Establishing Bipotential Human Lung Organoid Culture System and Differentiation to Generate Mature Alveolar and Airway Organoids
por: Chiu, Man Chun, et al.
Publicado: (2023)

A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant
por: Chiu, Man Chun, et al.
Publicado: (2022)

Human Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and Coronavirus
por: Zhao, Xiaoyu, et al.
Publicado: (2021)

Apical-Out Human Airway Organoids Modeling SARS-CoV-2 Infection
por: Chiu, Man Chun, et al.
Publicado: (2023)

Prime-Boost Vaccination With Covaxin/BBV152 Induces Heightened Systemic Cytokine and Chemokine Responses
por: Kumar, Nathella Pavan, et al.
Publicado: (2021)

Molecular species identification boosts bat diversity
por: Mayer, Frieder, et al.
Publicado: (2007)

Unraveling the macroevolution of horseshoe bats (Chiroptera: Rhinolophidae: Rhinolophus)
por: Guo, Wei-Jian, et al.
Publicado: (2023)

Heightening the awareness of headache disorders
Publicado: (2004)

Unraveling Human Brain Development and Evolution Using Organoid Models
por: Fernandes, Sarah, et al.
Publicado: (2021)

Heightened response to e-cigarettes in COPD
por: Bozier, Jack, et al.
Publicado: (2019)

Harnessing the Biology of Canine Intestinal Organoids to Heighten Understanding of Inflammatory Bowel Disease Pathogenesis and Accelerate Drug Discovery: A One Health Approach
por: Kopper, Jamie J., et al.
Publicado: (2021)

Can a relational mindset boost analogical retrieval?
por: Goldwater, Micah B., et al.
Publicado: (2019)

SPINK6 inhibits human airway serine proteases and restricts influenza virus activation
por: Wang, Dong, et al.
Publicado: (2021)

Unraveling the biochemistry and provenance of pupylation: a prokaryotic analog of ubiquitination
por: Iyer, Lakshminarayan M, et al.
Publicado: (2008)

Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
por: Urbaniak, Alicja, et al.
Publicado: (2022)

Novel Bat Alphacoronaviruses in Southern China Support Chinese Horseshoe Bats as an Important Reservoir for Potential Novel Coronaviruses
por: Lau, Susanna K.P., et al.
Publicado: (2019)

Differentiated human airway organoids to assess infectivity of emerging influenza virus
por: Zhou, Jie, et al.
Publicado: (2018)

Unravelling Mechanisms of Doxorubicin-Induced Toxicity in 3D Human Intestinal Organoids
por: Rodrigues, Daniela, et al.
Publicado: (2022)

Unraveling pathological mechanisms in neurological disorders: the impact of cell-based and organoid models
por: Langlie, Jake, et al.
Publicado: (2022)

Unravelling Pathophysiology of Neurological and Psychiatric Complications of COVID-19 Using Brain Organoids
por: Ng, Jing-Han, et al.
Publicado: (2021)

Heightened consciousness and curriculum in a time of crisis
por: Poindexter, Naomi Kikue, et al.
Publicado: (2021)

Extreme heat events heighten soil respiration
por: Anjileli, Hassan, et al.
Publicado: (2021)

Pandemic heightens the need to combat cardiovascular diseases
por: Regional Health– Europe, The Lancet
Publicado: (2021)

Blockade of PD-1 immunosuppression boosts CAR T-cell therapy
por: John, Liza B, et al.
Publicado: (2013)

Consequences of Exposure to War Violence: Discriminating Those with Heightened Risk for Aggression from Those with Heightened Risk for Post-Traumatic Stress Symptoms
por: Huesmann, L. Rowell, et al.
Publicado: (2023)

Intranasal Boosting with Spike Fc-RBD of Wild-Type SARS-CoV-2 Induces Neutralizing Antibodies against Omicron Subvariants and Reduces Viral Load in the Nasal Turbinate of Mice
por: Cai, Jian-Piao, et al.
Publicado: (2023)

Neurotransmission on Fire?: Metabolic Activation Heightens Effect of PBDEs
por: Barrett, Julia R.
Publicado: (2008)

Structural and kinetic basis for heightened immunogenicity of T cell vaccines
por: Chen, Ji-Li, et al.
Publicado: (2005)

PESTICIDES: Double Exposure Heightens Parkinson Disease Risk
por: Washam, Cynthia
Publicado: (2009)

Heightened risk of canine chocolate exposure at Christmas and Easter
por: Noble, Peter-John M, et al.
Publicado: (2017)

Eczema and Risk of Cardiovascular Disease: Heightened Awareness Needed
por: Fujiyoshi, Akira
Publicado: (2019)

Crowd Salience Heightens Tolerance to Healthy Facial Features
por: Brown, Mitch, et al.
Publicado: (2021)

Antibiotic-Selected Gene Amplification Heightens Metal Resistance
por: Hufnagel, David A., et al.
Publicado: (2021)

Pregnancy and the Opioid Crisis: Heightened Effects of COVID-19
por: White, Ashley, et al.
Publicado: (2022)

Homeostatic Depression Shows Heightened Sensitivity to Synaptic Calcium
por: Yeates, Catherine J., et al.
Publicado: (2021)

Reciprocity heightens academic performance in elementary school students
por: Candia, Cristian, et al.
Publicado: (2022)

Prior exposure of Arabidopsis seedlings to mechanical stress heightens jasmonic acid-mediated defense against necrotrophic pathogens
por: Brenya, Eric, et al.
Publicado: (2020)

Defense of COVID-19 by Human Organoids
por: Lv, Ting, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4uj92arb68utp1neqmp26uk68d