Rosiglitazone Reverses Inflammation in Epididymal White Adipose Tissue in Hormone-Sensitive Lipase-Knockout Mice

Hormone-sensitive lipase (HSL) plays a crucial role in intracellular lipolysis, and loss of HSL leads to diacylglycerol (DAG) accumulation, reduced FA mobilization, and impaired PPARγ signaling. Hsl knockout mice exhibit adipose tissue inflammation, but the underlying mechanisms are still not clear....

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Detalles Bibliográficos
Autores principales: Kotzbeck, Petra, Taschler, Ulrike, Haudum, Christoph, Foessl, Ines, Schoiswohl, Gabriele, Boulgaropoulos, Beate, Bounab, Kaddour, Einsiedler, Johanna, Pajed, Laura, Tilp, Anna, Schwarz, Anna, Eichmann, Thomas O., Obermayer-Pietsch, Barbara, Giordano, Antonio, Cinti, Saverio, Zechner, Rudolf, Pieber, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760656/
https://www.ncbi.nlm.nih.gov/pubmed/36273647
http://dx.doi.org/10.1016/j.jlr.2022.100305

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