Cargando…

Decreased xCT activity in patients associated with Helicobacter pylori infection

Objective: In animals, Helicobacter pylori (Hp)-induced gastric injury is accompanied by a decrease in the activity of the cysteine/glutamate transporter (xCT), which regulates extracellular glutamate levels. However, the impact of xCT activity in patients with Hp infection remains unclear. This stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ling, Li, Wen-Qun, Liu, Fen, Li, Yuan-Jian, Du, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760671/ https://www.ncbi.nlm.nih.gov/pubmed/36545313 http://dx.doi.org/10.3389/fphar.2022.1021655

Ejemplares similares

Sulfasalazine Sensitizes Polyhematoporphyrin-Mediated Photodynamic Therapy in Cholangiocarcinoma by Targeting xCT
por: Zheng, Yan-Wen, et al.
Publicado: (2021)

Acetylsalicylic acid reduces cigarette smoke withdrawal-induced anxiety in rats via modulating the expression of NFĸB, GLT-1, and xCT
por: Hammad, Alaa M., et al.
Publicado: (2023)

Participation of xCT in melanoma cell proliferation in vitro and tumorigenesis in vivo
por: Shin, Seung-Shick, et al.
Publicado: (2018)

Polyphyllin Ⅲ-Induced Ferroptosis in MDA-MB-231 Triple-Negative Breast Cancer Cells can Be Protected Against by KLF4-Mediated Upregulation of xCT
por: Zhou, Yulu, et al.
Publicado: (2021)

Structure‐Activity‐Relationship‐Aided Design and Synthesis of xCT Antiporter Inhibitors
por: Cirillo, Davide, et al.
Publicado: (2021)

xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation
por: Cai, Yi, et al.
Publicado: (2016)

Functional analysis of CD44 variants and xCT in canine tumours
por: Tanabe, Atsushi, et al.
Publicado: (2020)

The efficacy and mechanism of vonoprazan-containing triple therapy in the eradication of Helicobacter pylori
por: Zhang, Zinan, et al.
Publicado: (2023)

The Potential Use of Antibiotics Against Helicobacter pylori Infection: Biopharmaceutical Implications
por: Miri, Amir Hossein, et al.
Publicado: (2022)

Effect of Helicobacter pylori-Associated Chronic Gastritis on Autonomous Activity and Sleep Quality in Mice
por: Liu, Haihua, et al.
Publicado: (2022)

Effect of Acid Suppressants on Non–Helicobacter pylori Helicobacters Within Parietal Cells
por: Nakamura, Masahiko, et al.
Publicado: (2022)

Genomic analysis of xCT-regulatory network in KSHV + primary effusion lymphomas
por: Qin, Zhiqiang, et al.
Publicado: (2016)

xCT inhibition sensitizes tumors to γ-radiation via glutathione reduction
por: Cobler, Lara, et al.
Publicado: (2018)

xCT Inhibition Increases Sensitivity to Vorinostat in a ROS-Dependent Manner
por: Miyamoto, Keiko, et al.
Publicado: (2020)

Role of Vonoprazan in Helicobacter pylori Eradication Therapy in Japan
por: Sugimoto, Mitsushige, et al.
Publicado: (2019)

Role of the Outer Inflammatory Protein A/Cystine–Glutamate Transporter Pathway in Gastric Mucosal Injury Induced by Helicobacter pylori
por: Du, Jie, et al.
Publicado: (2020)

Overexpression of xCT induces up-regulation of 14-3-3β in Kaposi's sarcoma
por: Zeng, Yan, et al.
Publicado: (2010)

Flavonoids-Rich Plant Extracts Against Helicobacter pylori Infection as Prevention to Gastric Cancer
por: Ivyna de Araújo Rêgo, Renaly, et al.
Publicado: (2022)

STEAP3 Affects Ferroptosis and Progression of Renal Cell Carcinoma Through the p53/xCT Pathway
por: Ye, Cheng Lin, et al.
Publicado: (2022)

The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility
por: Shin, Chun-Shik, et al.
Publicado: (2017)

Growth differentiation factor 15 induces cisplatin resistance through upregulation of xCT expression and glutathione synthesis in gastric cancer
por: Wang, Sheng‐Fan, et al.
Publicado: (2023)

Impaired long-term potentiation and long-term memory deficits in xCT-deficient sut mice
por: Li, Yan, et al.
Publicado: (2012)

Tailored therapy for Helicobacter pylori eradication: A systematic review and meta-analysis
por: Ma, Qin, et al.
Publicado: (2022)

ROS Mediate xCT-Dependent Cell Death in Human Breast Cancer Cells under Glucose Deprivation
por: Chen, Mei-Chun, et al.
Publicado: (2020)

xCT knockdown in human breast cancer cells delays onset of cancer-induced bone pain
por: Ungard, Robert G, et al.
Publicado: (2019)

xCT, not just an amino-acid transporter: a multi-functional regulator of microbial infection and associated diseases
por: Dai, Lu, et al.
Publicado: (2015)

Unraveling the Novel Protective Effect of Patchouli Alcohol Against Helicobacter pylori-Induced Gastritis: Insights Into the Molecular Mechanism in vitro and in vivo
por: Lian, Da-wei, et al.
Publicado: (2018)

Salubrinal Enhances Cancer Cell Death during Glucose Deprivation through the Upregulation of xCT and Mitochondrial Oxidative Stress
por: Chen, Mei-Chun, et al.
Publicado: (2021)

Infection with Helicobacter pylori may predispose to atherosclerosis: role of inflammation and thickening of intima-media of carotid arteries
por: Aramouni, Karl, et al.
Publicado: (2023)

Butyrate reverses ferroptosis resistance in colorectal cancer by inducing c-Fos-dependent xCT suppression
por: He, Ying, et al.
Publicado: (2023)

Histone deacetylases inhibition by SAHA/Vorinostat normalizes the glioma microenvironment via xCT equilibration
por: Wolf, Ines M. L., et al.
Publicado: (2014)

Implication of the glutamate–cystine antiporter xCT in schizophrenia cases linked to impaired GSH synthesis
por: Fournier, M., et al.
Publicado: (2017)

Cystine/Glutamate Antiporter (xCT) Is Required for Chief Cell Plasticity After Gastric Injury
por: Meyer, Anne R., et al.
Publicado: (2019)

Chemotherapeutic xCT inhibitors sorafenib and erastin unraveled with the synaptic optogenetic function analysis tool
por: Dahlmanns, Marc, et al.
Publicado: (2017)

CD44 and xCT: The Silver Bullet for Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension?
por: Agrawal, Vineet, et al.
Publicado: (2019)

The Role of Cystine/Glutamate Antiporter SLC7A11/xCT in the Pathophysiology of Cancer
por: Jyotsana, Nidhi, et al.
Publicado: (2022)

A xCT role in tumour-associated ferroptosis shed light on novel therapeutic options
por: Criscuolo, Daniela, et al.
Publicado: (2022)

CIC reduces xCT/SLC7A11 expression and glutamate release in glioma
por: Park, Jong-Whi, et al.
Publicado: (2023)

The TNF-Alpha Inducing Protein is Associated With Gastric Inflammation and Hyperplasia in a Murine Model of Helicobacter pylori Infection
por: Morningstar-Wright, Lindsay, et al.
Publicado: (2022)

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
por: Koppula, Pranavi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_eeq03u87ck5vpe33ljqoa1bhgv