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Overexpression of SMS in the tumor microenvironment is associated with immunosuppression in hepatocellular carcinoma

Disorders of polyamine metabolism may contribute to the development of hepatocellular carcinoma (HCC), but the precise mechanism remains unknown. This study reports that spermine synthase (SMS), an enzyme involved in polyamine biosynthesis, is overexpressed in HCC and not associated with hepatitis v...

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Detalles Bibliográficos
Autores principales: Xiang, Lin, Piao, Longhuan, Wang, Dong, Qi, Li-Feng-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760682/
https://www.ncbi.nlm.nih.gov/pubmed/36544774
http://dx.doi.org/10.3389/fimmu.2022.974241

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