Cargando…

Integrated analysis of WGCNA and machine learning identified diagnostic biomarkers in dilated cardiomyopathy with heart failure

The etiologies and pathogenesis of dilated cardiomyopathy (DCM) with heart failure (HF) remain to be defined. Thus, exploring specific diagnosis biomarkers and mechanisms is urgently needed to improve this situation. In this study, three gene expression profiling datasets (GSE29819, GSE21610, GSE178...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Yihao, Yang, Xiaojing, Zu, Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760806/ https://www.ncbi.nlm.nih.gov/pubmed/36544902 http://dx.doi.org/10.3389/fcell.2022.1089915

Ejemplares similares

Susceptibility Modules and Genes in Hypertrophic Cardiomyopathy by WGCNA and ceRNA Network Analysis
por: Sun, Yifan, et al.
Publicado: (2022)

Identification of Biomarkers Associated with Heart Failure Caused by Idiopathic Dilated Cardiomyopathy Using WGCNA and Machine Learning Algorithms
por: Sun, Mengyi, et al.
Publicado: (2023)

Mitochondrial Function and Dysfunction in Dilated Cardiomyopathy
por: Ramaccini, Daniela, et al.
Publicado: (2021)

Circular RNA Expression for Dilated Cardiomyopathy in Hearts and Pluripotent Stem Cell–Derived Cardiomyocytes
por: Zhang, Yiyu, et al.
Publicado: (2021)

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy
por: Makarewich, Catherine A, et al.
Publicado: (2018)

Integrative Analysis of Biomarkers Through Machine Learning Identifies Stemness Features in Colorectal Cancer
por: Wei, Ran, et al.
Publicado: (2021)

Cardiac Overexpression of XIN Prevents Dilated Cardiomyopathy Caused by TNNT2 ΔK210 Mutation
por: Li, Bin, et al.
Publicado: (2021)

Ferroptosis Is a Potential Novel Diagnostic and Therapeutic Target for Patients With Cardiomyopathy
por: Zhai, Zhenyu, et al.
Publicado: (2021)

Zebrafish Heart Failure Models
por: Narumanchi, Suneeta, et al.
Publicado: (2021)

Reduction of Drosophila Mitochondrial RNase P in Skeletal and Heart Muscle Causes Muscle Degeneration, Cardiomyopathy, and Heart Arrhythmia
por: Saoji, Maithili, et al.
Publicado: (2022)

Integrative Analysis of DNA Methylation and Gene Expression to Determine Specific Diagnostic Biomarkers and Prognostic Biomarkers of Breast Cancer
por: Zhang, Ming, et al.
Publicado: (2020)

Identifying Protein Biomarkers in Blood for Alzheimer's Disease
por: Zhao, Tianyi, et al.
Publicado: (2020)

Machine learning identifies exosome features related to hepatocellular carcinoma
por: Zhu, Kai, et al.
Publicado: (2022)

Identification of Genome Sequences of Polyphosphate-Accumulating Organisms by Machine Learning
por: Liu, Bohan, et al.
Publicado: (2021)

Identify Inflammatory Bowel Disease-Related Genes Based on Machine Learning
por: Ye, Lili, et al.
Publicado: (2021)

mTORC2 protects the heart from high-fat diet-induced cardiomyopathy through mitochondrial fission in Drosophila
por: Liu, Peiduo, et al.
Publicado: (2022)

Identification and Validation of a Novel Prognosis Prediction Model in Adrenocortical Carcinoma by Integrative Bioinformatics Analysis, Statistics, and Machine Learning
por: Yan, Xin, et al.
Publicado: (2021)

Tubulin Post-translational Modifications: Potential Therapeutic Approaches to Heart Failure
por: Liu, Chang, et al.
Publicado: (2022)

Development and validation of risk prediction and neural network models for dilated cardiomyopathy based on WGCNA
por: Yu, Wei, et al.
Publicado: (2023)

KLF2 is a clinical diagnostic and treatment biomarker of breast cancer
por: Li, Ya-Zhao, et al.
Publicado: (2023)

Pan-cancer analysis identifies YTHDF2 as an immunotherapeutic and prognostic biomarker
por: Liu, Weiwei, et al.
Publicado: (2022)

An Integrated Analysis of the Identified PRPF19 as an Onco-immunological Biomarker Encompassing the Tumor Microenvironment, Disease Progression, and Prognoses in Hepatocellular Carcinoma
por: Yang, Ming, et al.
Publicado: (2022)

Integrated Bioinformatical Analysis Identifies GIMAP4 as an Immune-Related Prognostic Biomarker Associated With Remodeling in Cervical Cancer Tumor Microenvironment
por: Xu, Fangfang, et al.
Publicado: (2021)

Mitophagy in Diabetic Cardiomyopathy: Roles and Mechanisms
por: Zheng, Haoxiao, et al.
Publicado: (2021)

mtDNA Heteroplasmy at the Core of Aging-Associated Heart Failure. An Integrative View of OXPHOS and Mitochondrial Life Cycle in Cardiac Mitochondrial Physiology
por: Elorza, Alvaro A., et al.
Publicado: (2021)

Role of Extracellular Vesicles as Potential Diagnostic and/or Therapeutic Biomarkers in Chronic Cardiovascular Diseases
por: Martin-Ventura, Jose Luis, et al.
Publicado: (2022)

Exosomal microRNA panel as a diagnostic biomarker in patients with hepatocellular carcinoma
por: Yang, Jingwen, et al.
Publicado: (2022)

WGCNA combined with machine learning algorithms for analyzing key genes and immune cell infiltration in heart failure due to ischemic cardiomyopathy
por: Kong, XiangJin, et al.
Publicado: (2023)

Targeting Orai1-Mediated Store-Operated Ca(2+) Entry in Heart Failure
por: Luo, Rui, et al.
Publicado: (2020)

Identification and validation of the diagnostic signature associated with immune microenvironment of acute kidney injury based on ferroptosis-related genes through integrated bioinformatics analysis and machine learning
por: Chen, Yalei, et al.
Publicado: (2023)

HIV Neuroinflammation: The Role of Exosomes in Cell Signaling, Prognostic and Diagnostic Biomarkers and Drug Delivery
por: Mahajan, Supriya D., et al.
Publicado: (2021)

Single-Cell RNA Sequencing and Quantitative Proteomics Analysis Elucidate Marker Genes and Molecular Mechanisms in Hypoplastic Left Heart Patients With Heart Failure
por: Ma, Li, et al.
Publicado: (2021)

Integrated proteome sequencing, bulk RNA sequencing and single-cell RNA sequencing to identify potential biomarkers in different grades of intervertebral disc degeneration
por: Yang, Xiao, et al.
Publicado: (2023)

Bioinformatic profiling identifies the glutaminase to be a potential novel cuproptosis-related biomarker for glioma
por: Ouyang, Zhen, et al.
Publicado: (2022)

Discovering new peripheral plasma biomarkers to identify cognitive decline in type 2 diabetes
por: Yu, Haitao, et al.
Publicado: (2022)

PGC-1α-Mediated Mitochondrial Quality Control: Molecular Mechanisms and Implications for Heart Failure
por: Chen, Lei, et al.
Publicado: (2022)

Hydrogen Sulfide Plays an Important Role in Diabetic Cardiomyopathy
por: Zhao, Shizhen, et al.
Publicado: (2021)

High-Throughput Metabolomics for Discovering Potential Biomarkers and Identifying Metabolic Mechanisms in Aging and Alzheimer’s Disease
por: Xie, Kun, et al.
Publicado: (2021)

Metabolite Profiling of Pig Seminal Plasma Identifies Potential Biomarkers for Sperm Resilience to Liquid Preservation
por: Mateo-Otero, Yentel, et al.
Publicado: (2021)

Comprehensive analysis to identify the neurotransmitter receptor-related genes as prognostic and therapeutic biomarkers in hepatocellular carcinoma
por: Wang, Xiaoqiang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1r4iooptljh76ujahgsmlkgbin