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Novel protocol to establish the myocardial infarction model in rats using a combination of medetomidine-midazolam-butorphanol (MMB) and atipamezole

BACKGROUND: Myocardial infarction (MI) is one of the most common cardiac problems causing deaths in humans. Previously validated anesthetic agents used in MI model establishment are currently controversial with severe restrictions because of ethical concerns. The combination between medetomidine, mi...

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Detalles Bibliográficos
Autores principales: Farag, Ahmed, Mandour, Ahmed S., Hamabe, Lina, Yoshida, Tomohiko, Shimada, Kazumi, Tanaka, Ryou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760920/
https://www.ncbi.nlm.nih.gov/pubmed/36544554
http://dx.doi.org/10.3389/fvets.2022.1064836