Repeated dosing improves oncolytic rhabdovirus therapy in mice via interactions with intravascular monocytes

There is debate in the field of oncolytic virus (OV) therapy, whether a single viral dose, or multiple administrations, is better for tumor control. Using intravital microscopy, we describe the fate of vesicular stomatitis virus (VSV) delivered systemically as a first or a second dose. Following pri...

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Detalles Bibliográficos
Autores principales: Naumenko, Victor, Rajwani, Jahanara, Turk, Madison, Zhang, Chunfen, Tse, Mandy, Davis, Rachelle P., Kim, Daesun, Rakic, Andrea, Dastidar, Himika, Van, Shinia, Mah, Laura K., Kaul, Esha K., Chekhonin, Vladimir P., Mahoney, Douglas J., Jenne, Craig N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761050/
https://www.ncbi.nlm.nih.gov/pubmed/36536097
http://dx.doi.org/10.1038/s42003-022-04254-3

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