BAG3 promotes autophagy and suppresses NLRP3 inflammasome activation in Parkinson’s disease

BACKGROUND: Neuroinflammation mediated by microglia plays a key role in the pathogenesis of Parkinson’s disease (PD), and our previous studies showed this was significantly inhibited by enhanced autophagy. In the autophagy pathway, Bcl2-associated athanogene (BAG)3 is a prominent co-chaperone, and w...

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Detalles Bibliográficos
Autores principales: Ying, Zhong-Ming, Lv, Qian-Kun, Yao, Xiao-Yu, Dong, An-Qi, Yang, Ya-Ping, Cao, Yu-Lan, Wang, Fen, Gong, Ai-Ping, Liu, Chun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761134/
https://www.ncbi.nlm.nih.gov/pubmed/36544667
http://dx.doi.org/10.21037/atm-22-5159

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