Clostridioides difficile Induced Rhabdomyolysis Associated With Decompensated Cirrhosis

Rhabdomyolysis (RBD) occurs secondary to tissue injury, resulting in (muscle) cell lysis and release of intracellular electrolytes and proteins into circulation. An elevation in the muscle enzyme, creatine kinase (CK), is a diagnostic marker and indicates muscle breakdown. Symptoms include dark urin...

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Detalles Bibliográficos
Autores principales: Dungan, William, Young, Gabrielle, Collins, Bradley, Romano, John, Honko, Nicholas, Rockey, Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Case Report - AFMR Member
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761200/
https://www.ncbi.nlm.nih.gov/pubmed/36519690
http://dx.doi.org/10.1177/23247096221132249
Descripción
Sumario:Rhabdomyolysis (RBD) occurs secondary to tissue injury, resulting in (muscle) cell lysis and release of intracellular electrolytes and proteins into circulation. An elevation in the muscle enzyme, creatine kinase (CK), is a diagnostic marker and indicates muscle breakdown. Symptoms include dark urine caused by release of myoglobin, myalgias, and acute kidney injury (AKI). RBD is categorized as (1) traumatic, (2) nontraumatic exertional (ie, metabolic myopathies), or (3) non-exertional and non-traumatic. Clostridioides difficile (CD) has been previously reported to cause RBD, but the risk factors, pathogenesis, and recommended treatment regimen remain unclear.

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