Clostridioides difficile Induced Rhabdomyolysis Associated With Decompensated Cirrhosis

Rhabdomyolysis (RBD) occurs secondary to tissue injury, resulting in (muscle) cell lysis and release of intracellular electrolytes and proteins into circulation. An elevation in the muscle enzyme, creatine kinase (CK), is a diagnostic marker and indicates muscle breakdown. Symptoms include dark urin...

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Autores principales: Dungan, William, Young, Gabrielle, Collins, Bradley, Romano, John, Honko, Nicholas, Rockey, Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Case Report - AFMR Member
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761200/
https://www.ncbi.nlm.nih.gov/pubmed/36519690
http://dx.doi.org/10.1177/23247096221132249
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author Dungan, William
Young, Gabrielle
Collins, Bradley
Romano, John
Honko, Nicholas
Rockey, Don
author_facet Dungan, William
Young, Gabrielle
Collins, Bradley
Romano, John
Honko, Nicholas
Rockey, Don
author_sort Dungan, William
collection PubMed
description Rhabdomyolysis (RBD) occurs secondary to tissue injury, resulting in (muscle) cell lysis and release of intracellular electrolytes and proteins into circulation. An elevation in the muscle enzyme, creatine kinase (CK), is a diagnostic marker and indicates muscle breakdown. Symptoms include dark urine caused by release of myoglobin, myalgias, and acute kidney injury (AKI). RBD is categorized as (1) traumatic, (2) nontraumatic exertional (ie, metabolic myopathies), or (3) non-exertional and non-traumatic. Clostridioides difficile (CD) has been previously reported to cause RBD, but the risk factors, pathogenesis, and recommended treatment regimen remain unclear.
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spelling pubmed-97612002022-12-20 Clostridioides difficile Induced Rhabdomyolysis Associated With Decompensated Cirrhosis Dungan, William Young, Gabrielle Collins, Bradley Romano, John Honko, Nicholas Rockey, Don J Investig Med High Impact Case Rep Case Report - AFMR Member Rhabdomyolysis (RBD) occurs secondary to tissue injury, resulting in (muscle) cell lysis and release of intracellular electrolytes and proteins into circulation. An elevation in the muscle enzyme, creatine kinase (CK), is a diagnostic marker and indicates muscle breakdown. Symptoms include dark urine caused by release of myoglobin, myalgias, and acute kidney injury (AKI). RBD is categorized as (1) traumatic, (2) nontraumatic exertional (ie, metabolic myopathies), or (3) non-exertional and non-traumatic. Clostridioides difficile (CD) has been previously reported to cause RBD, but the risk factors, pathogenesis, and recommended treatment regimen remain unclear. SAGE Publications 2022-12-15 /pmc/articles/PMC9761200/ /pubmed/36519690 http://dx.doi.org/10.1177/23247096221132249 Text en © 2022 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report - AFMR Member
Dungan, William
Young, Gabrielle
Collins, Bradley
Romano, John
Honko, Nicholas
Rockey, Don
Clostridioides difficile Induced Rhabdomyolysis Associated With Decompensated Cirrhosis
title Clostridioides difficile Induced Rhabdomyolysis Associated With Decompensated Cirrhosis
title_full Clostridioides difficile Induced Rhabdomyolysis Associated With Decompensated Cirrhosis
title_fullStr Clostridioides difficile Induced Rhabdomyolysis Associated With Decompensated Cirrhosis
title_full_unstemmed Clostridioides difficile Induced Rhabdomyolysis Associated With Decompensated Cirrhosis
title_short Clostridioides difficile Induced Rhabdomyolysis Associated With Decompensated Cirrhosis
title_sort clostridioides difficile induced rhabdomyolysis associated with decompensated cirrhosis
topic Case Report - AFMR Member
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761200/
https://www.ncbi.nlm.nih.gov/pubmed/36519690
http://dx.doi.org/10.1177/23247096221132249
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