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Combined computational approaches for developing new anti-Alzheimer drug candidates: 3D-QSAR, molecular docking and molecular dynamics studies of liquiritigenin derivatives

Butyrylcholinesterase is an acetylcholine-degrading enzyme involved in the memorization process, which is becoming an interesting target for the symptomatic treatment of Alzheimer's disease. In the present investigation, the structure–activity relationship of a set of Liquiritigenin derivatives...

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Detalles Bibliográficos
Autores principales:	Nour, Hassan, Daoui, Ossama, Abchir, Oussama, ElKhattabi, Souad, Belaidi, Salah, Chtita, Samir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761610/ https://www.ncbi.nlm.nih.gov/pubmed/36544815 http://dx.doi.org/10.1016/j.heliyon.2022.e11991

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