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Rare fatal poisoning through dermal exposure to paraquat

Paraquat skin contact occurs less frequently and is rarely fatal. This article reports a case of a 45-year-old man who presented with dysphagia, respiratory distress and grade two, and third skin burns focusing on the upper body after accidental exposure to paraquat. He was admitted to the hospital...

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Autores principales: Eizadi-Mood, Nastaran, Haddad, Shadi, Mirmoghtadaei, Parisa, Mahvari, Razieh, Meamar, Rokhsareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761795/
https://www.ncbi.nlm.nih.gov/pubmed/36545010
http://dx.doi.org/10.1177/2050313X221139621
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author Eizadi-Mood, Nastaran
Haddad, Shadi
Mirmoghtadaei, Parisa
Mahvari, Razieh
Meamar, Rokhsareh
author_facet Eizadi-Mood, Nastaran
Haddad, Shadi
Mirmoghtadaei, Parisa
Mahvari, Razieh
Meamar, Rokhsareh
author_sort Eizadi-Mood, Nastaran
collection PubMed
description Paraquat skin contact occurs less frequently and is rarely fatal. This article reports a case of a 45-year-old man who presented with dysphagia, respiratory distress and grade two, and third skin burns focusing on the upper body after accidental exposure to paraquat. He was admitted to the hospital 6 days after the first contact. The urine sodium dithionate test was strongly positive. The O(2) saturation at admission was 52%, which reached 91% with a bag valve mask. Rising blood liver enzymes, urea, creatinine, and respiratory acidosis in the venous blood gas analysis were observed in the lab data. In the course of hospitalization, the patient was intubated due to oxygen level dropping. Evidence of acute respiratory distress syndrome and decreased level of consciousness was also observed. However, despite treatment with corticosteroids, antioxidants, and hemodialysis, he died on the fourth day of hospitalization. It is concluded that dermal exposure with paraquat could be life-threatening if the patient presented late with organ involvement.
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spelling pubmed-97617952022-12-20 Rare fatal poisoning through dermal exposure to paraquat Eizadi-Mood, Nastaran Haddad, Shadi Mirmoghtadaei, Parisa Mahvari, Razieh Meamar, Rokhsareh SAGE Open Med Case Rep Case Report Paraquat skin contact occurs less frequently and is rarely fatal. This article reports a case of a 45-year-old man who presented with dysphagia, respiratory distress and grade two, and third skin burns focusing on the upper body after accidental exposure to paraquat. He was admitted to the hospital 6 days after the first contact. The urine sodium dithionate test was strongly positive. The O(2) saturation at admission was 52%, which reached 91% with a bag valve mask. Rising blood liver enzymes, urea, creatinine, and respiratory acidosis in the venous blood gas analysis were observed in the lab data. In the course of hospitalization, the patient was intubated due to oxygen level dropping. Evidence of acute respiratory distress syndrome and decreased level of consciousness was also observed. However, despite treatment with corticosteroids, antioxidants, and hemodialysis, he died on the fourth day of hospitalization. It is concluded that dermal exposure with paraquat could be life-threatening if the patient presented late with organ involvement. SAGE Publications 2022-12-17 /pmc/articles/PMC9761795/ /pubmed/36545010 http://dx.doi.org/10.1177/2050313X221139621 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Eizadi-Mood, Nastaran
Haddad, Shadi
Mirmoghtadaei, Parisa
Mahvari, Razieh
Meamar, Rokhsareh
Rare fatal poisoning through dermal exposure to paraquat
title Rare fatal poisoning through dermal exposure to paraquat
title_full Rare fatal poisoning through dermal exposure to paraquat
title_fullStr Rare fatal poisoning through dermal exposure to paraquat
title_full_unstemmed Rare fatal poisoning through dermal exposure to paraquat
title_short Rare fatal poisoning through dermal exposure to paraquat
title_sort rare fatal poisoning through dermal exposure to paraquat
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761795/
https://www.ncbi.nlm.nih.gov/pubmed/36545010
http://dx.doi.org/10.1177/2050313X221139621
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