Gene knockdown by structure defined single-stem loop small non-coding RNAs with programmable regulatory activities

Gene regulation by trans-acting small RNAs (sRNAs) has considerable advantages over other gene regulation strategies. However, synthetic sRNAs mainly take natural sRNAs (MicC or SgrS) as backbones and comprise three functional elements folding into two or more stem-loop structures: an mRNA base pair...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Yin, Guobin, Weng, Huanjiao, Zhang, Luyao, Du, Guocheng, Chen, Jian, Kang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761848/
https://www.ncbi.nlm.nih.gov/pubmed/36582457
http://dx.doi.org/10.1016/j.synbio.2022.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761848/
https://www.ncbi.nlm.nih.gov/pubmed/36582457
http://dx.doi.org/10.1016/j.synbio.2022.11.006

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